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Preparation of rifampicin/poly(d,l-lactice) nanoparticles for sustained release by supercritical assisted atomization technique
(Elsevier, 2014-11)
In this work supercritical assisted atomization (SAA) process was used for the co-precipitation of poly(d,l-lactide) (PDLLA) and rifampicin (RIF) as nanoparticles for sustained release applications. The effect of the ...
Nanomedicine: Past, present and future - A global perspective.
(Elsevier Inc, 2015-12-18)
Nanomedicine is an emerging and rapidly evolving field and includes the use of nanoparticles for diagnosis and therapy of a variety of diseases, as well as in regenerative medicine. In this mini-review, leaders in the field ...
Microalgae: An alternative natural source of bioavailable omega-3 DHA for promotion of mental health in East Africa
(Elsevier, 2019-10-11)
Mental health illness associated with poor nutrition is a serious public concern worldwide. The most at risk individuals are children and adolescents in the developing world. Deficiencies in omega-3 DHA fatty acids have ...
Review of Agricultural and Rural Development System Models and Frameworks to Support Farming as a Business via Benchmarking: The Case of Tanzania
(International Journal of Computing and Digital Systems, 2019-11-01)
This paper presents a review of the current state of agricultural and rural development (ARD) system frameworks, focusing on their capabilities and limitations to support farming-as-a-business via benchmarking (FAABB). ...
Mobile application development framework to support farming as a business via benchmarking: the case of Tanzania
(International Journal of Advanced Computer Research (IJACR), 2019-11)
Contributions from various researchers and scholars have made major advances relevant to a wide range of mobile
applications at various scales. Although current agricultural and rural development (ARD) systems have features ...
Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies
(MDPI, 2018-06-12)
Clinical applications of many small molecules are limited due to poor solubility and lack
of controlled release besides lack of other desirable properties. Experimental and computational
studies have reported on the ...
Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis
(Elsevier, 2015-06-06)
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development
of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities
(Springer, 2015-03-28)
Purpose There is significant interest in the application of nanoparticles
to deliver immunostimulatory signals to cells.We hypothesized
that curdlan (immune stimulating polymer) could be conjugated
to PLGA and nanoparticles ...
Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles
(Dovepress, 2014-08-11)
Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- ...
Comparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes
(Taylor & Francis Group., 2019-04-22)
Nanoparticles (NPs) have gained importance in addressing drug delivery challenges across biological
barriers. Here, we reformulated pentamidine, a drug used to treat Human African Trypanosomiasis
(HAT) in polymer based ...