Browsing Life sciences and Bio-engineering by Issue Date
Now showing items 1-20 of 1197
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Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves
(Elsevier Ltd, 1995-11)A bioassay was used to measure erythropoietin (EPO) concentrations in calves with haemorrhagic anaemia due to blood loss and in calves with anaemia due to Trypanosoma congolense infection. The bioactivity of EPO was measured ... -
Modifications of the hydrophilicity of heterocyclic methacrylate copolymers for protein release
(Elsevier, 1995-12)A series of copolymers comprising ethyl methacrylate (EM) and tetrahydrofurfuryl methacrylate (THFMA) gelled with either THFMA monomer or hydroxyethyl methacrylate (HEMA) monomer have been developed. In this paper, we ... -
CD5+ B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense-infected cattle
(Blackwell Science Ltd, 1997)Mice infected with African trypanosomes produce exceptionally large amounts of serum IgM, a major part of which binds to non-trypanosome antigens such as trinitrophenol and single-strand DNA. In this paper, we describe ... -
The water uptake of poly(tetrahydrofurfuryl methacrylate)
(Elsevier, 1999-03)Poly(tetrahydrofurfuryl methacrylate) possesses some unique characteristics with respect to its biocompatibility and behaviour in water. The water uptake is high (>70%) and very slow (over 3 yr), but the material remains ... -
Trypanosome non-specific IgM antibodies detected in serum of Trypanosoma congolense-infected cattle are polyreactive
(Elsevier Science, 1999-07-01)Serum Ig from Trypanosoma congolense-infected cattle were affinity-purified using immobilised trypanosome or non-trypanosome antigens (ß-galactosidase, cytochrome C and ferritin). The bound and unbound IgG and IgM fractions ... -
A polymeric system for the intra-oral delivery of an anti-fungal agent
(Elsevier Science Ltd., 2001)Oral candidal infections are often persistent and intractable and thus the aim of this study was to develop a polymeric sustained release device to improve the topical treatment of these infections. A self curing system ... -
Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
(Blackwell Science Ltd, 2003)The first visible response in livestock to the bite of a trypanosomeinfected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated ... -
Mycobacterium bovis in rural Tanzania: Risk factors for infection in human and cattle populations
(Elsevier Ltd., 2007-01)Although bovine tuberculosis is widespread throughout Africa, very little is known about risk factors for Mycobacterium bovis infection in either human or cattle populations. A human case–control study was conducted in ... -
Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer
(Springer Nature, 2007-01-23)Introduction Tamoxifen therapy reduces the risk of recurrence and prolongs the survival of oestrogen-receptor-positive patients with breast cancer. Even if most patients benefit from tamoxifen, many breast tumours either ... -
Modeling the proteome of a Marek's disease transformed cell line: a natural animal model for CD30 overexpressing lymphomas.
(Proteomics, 2007-04-18)Marek's disease (MD) in the chicken, caused by the highly infectious MD alpha-herpesvirus (MDV), is both commercially important and a unique, naturally occurring model for human T-cell lymphomas overexpressing the Hodgkin's ... -
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands
(Elsevier, 2008)Single-stranded viral RNA (ssRNA) was recently identified as the natural ligand for TLR7 and TLR8. ssRNA sequences from viruses, as well as their synthetic analogues stimulate innate immune responses in immune cells from ... -
The neoplastically transformed (CD30hi) Marek’s disease lymphoma cell phenotype most closely resembles T-regulatory cells
(Springer-Verlag, 2008-02-07)Introduction Marek’s disease (MD), a herpesvirus-induced lymphoma of chickens is a unique natural model of CD30- overexpressing (CD30hi) lymphoma. We have previously proposed that the CD30hi neoplastically transformed ... -
Genotype-Dependent Tumor Regression in Marek’s Disease Mediated at the Level of Tumor Immunity
(Springer, 2008-03-18)Marek’s disease (MD) of chickens is a unique natural model of Hodgkin’s and Non Hodgkin’s lymphomas in which the neoplastically-transformed cells over-express CD30 (CD30hi) antigen. All chicken genotypes can be infected ... -
Germination of Invasive Plant Seeds after Digestion by Horses in California
(Natural Areas Journal, 2008-10)Using a unique sterile design intended to eliminate outside seed contamination of horse feces, we investigated whether weed seeds germinate after digestion by horses. Feces were collected from selected National Parks and ... -
Potential of treating tuberculosis with a polymeric nano-drug delivery system
(Elsevier, 2008-12-18)An effective therapeutic regimen is available for the treatment of tuberculosis (TB), however in developing countries; patient non-compliance due to high dose frequency and the lengthy duration of treatment, presents a ... -
Rooting and growth potential of Leucadendron laxum (proteaceae) using different rooting mediums and indoleacetic acid growth regulators
(Sabinet African Journals About Sabin, 2009-01-01)Leucadendron laxum (Proteaceae) is a South African plant species with a high commercial value as a flowering potted plant. Limited research information on the culture and propagation of this species is available in South ... -
Occurrence of patulin in various fruit juices from South Korea: An exposure assessment
(Springer Nature Switzerland AG., 2010-02-28)To determine patulin in various fruit juices, high performance liquid chromatography (HPLC) method was optimized and validated. For validation of HPLC method, a linearity, accuracy, precision, detection limit, and ... -
Evaluation of housing as a means to protect cattle from Culicoides biting midges, the vectors of bluetongue virus.
(The Royal Entomological Society, 2010-03-01)The housing of animals at night was investigated as a possible means of protecting them from attack by Culicoides biting midges (Diptera: Ceratopogonidae), the vectors of bluetongue. Light-trap catches of Culicoides were ... -
In vivo uptake and acute immune response to orally administered chitosan and PEG coated PLGA nanoparticles
(Elsevier, 2010-09-17)Nanoparticulate drug delivery systems offer great promise in addressing challenges of drug toxicity, poor bioavailability and non-specificity for a number of drugs. Much progress has been reported for nano drug delivery ... -
In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems
(Elsevier Inc., 2010-10)The remarkable physicochemical properties of particles in the nanometer range have been proven to address many challenges in the field of science. However, the possible toxic effects of these particles have raised some ...
