Browsing Life sciences and Bio-engineering by Issue Date
Now showing items 21-40 of 843
-
Enhanced use of beneath-canopy vegetation by grazing ungulates in African savannahs
(Elsevier B.V., 2010-12)The cover of large trees in African savannahs is rapidly declining, mainly due to human land-use practices. Trees improve grass nutrient quality and contribute to species and structural diversity of savannah vegetation. ... -
Cholinergic neurons regulate secretion of glial cell line-derived neurotrophic factor by skeletal muscle cells in culture.
(Elsevier, 2011-05-16)Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent survival factor for both central and peripheral neurons. GDNF has been shown to be a potent survival factor for motor neurons during ... -
A preliminary study of T-2 and HT-2 toxins in cereals sold in traditional market in South Korea
(Elsevier Ltd., 2011-08)Fusarium species are responsible for the production of harmful trichothecenes mycotoxins in cereals. These mycotoxins are cytotoxic, potentially immunosuppressive and potent fast-acting inhibitors of protein and nucleic ... -
Plague and climate: scales matter.
(PLoS Pathogens, 2011-09-01)Plague is enzootic in wildlife populations of small mammals in central and eastern Asia, Africa, South and North America, and has been recognized recently as a reemerging threat to humans. Its causative agent Yersinia ... -
Production of Coturnix quail immunoglobulins Y (IgYs) against Vibrio parahaemolyticus and Vibrio vulnificus
(Springer Nature Switzerland AG., 2011-12-31)Production of chicken immunoglobulins Y (IgYs) and their applications in prophylactic, therapeutic, detection of microbial contaminants and as a diagnostic tool has been widely studied with limited information from other ... -
Exercise-dependent regulation of glial cell line-derived neurotrophic factor (GDNF) expression in skeletal muscle and its importance for the neuromuscular system
(Higher Education Press and Springer-Verlag Berlin Heidelberg, 2012)The focus of this review is to highlight the importance of glial cell line-derived neurotrophic factor (GDNF) for the motor nervous system. GDNF is the most potent survival factor for motor neurons, where it enhances maintenance ... -
Nuclear Factor kappa B is central to Marek’s Disease herpesvirus induced neoplastic transformation of CD30 expressing lymphocytes in-vivo
(BMC Systems Biology, 2012)Background: Marek’s Disease (MD) is a hyperproliferative, lymphomatous, neoplastic disease of chickens caused by the oncogenic Gallid herpesvirus type 2 (GaHV-2; MDV). Like several human lymphomas the neoplastic MD lymphoma ... -
Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration
(Elsevier B.V., 2012-03-15)The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ... -
Resistance of Bacillus cereus and its enterotoxin genes in ready-to-eat foods to γ-irradiation
(Springer Nature Switzerland AG., 2012-04-30)This study was investigated the resistance of Bacillus cereus ATCC 13752 and its enterotoxin coding genes in cereals, vegetables, and tryptic soy broth to γ-irradiation. Screening for enterotoxin coding genes, viability ... -
The effect of plant extracts as seed treatments to control bacterial leaf spot of tomato in Tanzania
(Springer Nature, 2012-05-05)Bacterial leaf spot (BLS) caused by seed-borne xanthomonads is a serious disease of tomato (Solanum lycopersicum L.), causing significant losses in both yield and quality. To identify more effective control measures, we ... -
Porous Polyethylene Composite as Biomass Carrier for Red Pigment Production Using Monosodium Glutamate Wastewater as Medium
(American Scientific Publishers, 2012-10-01)Abundant acidic wastewater from monosodium glutamate production is difficult to treat, leading to serious water pollution. Utilization of monosodium glutamate wastewater (MSGW) with high concentration of COD (33170 mg/L) ... -
Design and formulation of nano-sized spray dried efavirenz-part I: influence of formulation parameters
(Springer Nature Switzerland AG., 2012-10-25)Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 μg/mL), which leads to a ... -
Preparation of rifampicin/lactose microparticle composites by a supercritical antisolvent-drug excipient mixing technique for inhalation delivery
(Elsevier, 2013-02)Rifampicin (RIF) is precipitated in the presence of inhalable lactose particles using a supercritical antisolvent-drug excipient mixing (SAS-DEM) technique to create RIF/lactose microparticle composites intended to improve ... -
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid.
(Elsevier B.V., 2013-02-28)Poly-(dl-lactic-co-glycolic) acid (PLGA) nanoparticles were prepared by a double emulsion solvent evaporation spray-drying technique and coated with polyethylene glycol (PEG 1% v/v). The PLGA nanoparticles had a small size ... -
Production of mouse anti-quail IgY and subsequent labeling with horseradish peroxidase using cyanuric chloride.
(J. Microbiol. Biotechnol, 2013-04-01)Polyclonal antibodies labeled with a tracer have been commonly used as secondary antibodies in immunochemical assays to quantify the concentration of antibody-antigen complexes. The majority of these antibodies conjugated ... -
Efficiency of fractionated γ-irradiation doses to eliminate vegetative cells and spores of Bacillus cereus from raw rice
(2013-04-30)Efficacy of fractionated γ-irradiation to eliminate vegetative and spore forms of Bacillus cereus from raw rice was studied. Viable bacteria and spores count performed after irradiation treatment revealed that vegetative ... -
Nanoencapsulation of water-soluble drug, lamivudine, using a double emulsion spray-drying technique for improving HIV treatment
(Springer Nature Switzerland AG., 2013-10-22)Current treatments available for human immunodeficiency virus, namely antiretrovirals, do not completely eradicate the virus from the body, leading to life-time commitment. Many antiretrovirals suffer drawbacks from ... -
Understanding the persistence of plague foci in Madagascar.
(PLOS Neglected Tropical Diseases, 2013-11-01)Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: ... -
State of the art and future directions in nanomedicine for tuberculosis.
(Expert Opinion on Drug Delivery, 2013-12-01)Introduction: Tuberculosis (TB) ranks the second leading cause of death from an infectious disease worldwide. However, treatment of TB is affected by poor patient compliance due to the requirement for daily drug administration, ... -
Assessing the Sustainability of Different Small-Scale Livestock Production Systems in the Afar Region, Ethiopia
(MDPI, 2013-12-02)Livestock production is a key income source in eastern Africa, and 80% of the total agricultural land is used for livestock herding. Hence, ecological and socio-economically sustainable rangeland management is crucial. Our ...
