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The empirical estimates and derived parameters used to calibrate the transmission model for villages testing nets or nets and larviciding in the Kenyan trial [34]. Crude estimates for the total reduction in adult mosquitoes at the village level, the global estimates of species reductions according to the GLMM analysis (Eqs 4–7). The relative species compositions in each village that are used to weight the percentage reductions in adult densities simulated in the transmission model, the village-level statistically estimated ranges in reductions in vectors, the baseline prevalences as measured using microscopy in the ba
(PLOS Pathogens, 2025-07-28) Sherrard-Smith, Ellie; Fillinger, Ulrike; Tia, Jean-Philippe; Winskill, Peter; Koudou, Benjamin; Tchicaya, Emile; Sanou, Antoine; Okumu, Fredros; Opiyo, Mercy; Majambere, Silas; Hamlet, Arran; Charles, Giovanni; Lambert, Ben; Churcher, Thomas
The empirical estimates and derived parameters used to calibrate the transmission model for villages testing nets or nets and larviciding in the Kenyan trial [34]. Crude estimates for the total reduction in adult mosquitoes at the village level, the global estimates of species reductions according to the GLMM analysis (Eqs 4–7). The relative species compositions in each village that are used to weight the percentage reductions in adult densities simulated in the transmission model, the village-level statistically estimated ranges in reductions in vectors, the baseline prevalences as measured using microscopy in the ba
The data estimates and derived parameters used to calibrate the transmission model for an ITN-only and ITN plus larviciding trial in Côte d’Ivoire [35]. Crude estimates for the total reduction in larval and adult mosquitoes at the village level (derived from empirical data), the global estimates of vector density reductions according to the GLMM analysis (Eqs 4–7). The relative species compositions in each village that are used to weight the percentage reductions in adult densities simulated in the transmission model, the village-level statistically estimated ranges in reductions in vectors, the baseline and follow up
(PLOS One, 2025-07-28) Sherrard-Smith, Ellie; Fillinger, Ulrike; Tia, Jean-Philippe; Winskill, Peter; Koudou, Benjamin; Tchicaya, Emile; Sanou, Antoine; Okumu, Fredros; Opiyo, Mercy; Majambere, Silas; Hamlet, Arran; Charles, Giovanni; Lambert, Ben; Churcher, Thomas
The data estimates and derived parameters used to calibrate the transmission model for an ITN-only and ITN plus larviciding trial in Côte d’Ivoire [35]. Crude estimates for the total reduction in larval and adult mosquitoes at the village level (derived from empirical data), the global estimates of vector density reductions according to the GLMM analysis (Eqs 4–7). The relative species compositions in each village that are used to weight the percentage reductions in adult densities simulated in the transmission model, the village-level statistically estimated ranges in reductions in vectors, the baseline and follow up
Summary statistics of linear models for maize fumonisins from the 2015 survey.
(Frontiers, 2025-01-13) Stafstrom, William; Ngure, Francis; Mshanga, John; Wells, Henry; Nelson, Rebecca; Mischler, John
Summary statistics of linear models for maize fumonisins from the 2015 survey.
Modeling the role of environmental contamination and non-human primates in the transmission dynamics of Marburg virus disease
(Springer Nature, 2025-10-24) Damiano, Ester; Irunde, Jacob; Mayengo, Maranya
Marburg virus disease is a highly virulent zoonotic infection, characterized by sporadic outbreaks and high mortality rates posing a significant public health threat. Despite strong evidence that MVD is zoonotic, the roles of non-human primates and contaminated environments in its transmission dynamics remain under-explored. This study investigates the role of environmental contamination and non-human primates in the transmission dynamics of MVD. A deterministic mathematical model incorporating humans, bats, monkeys, and environmental viral loads is employed to analyze MVD transmission. The basic reproduction number () is derived to examine the stability properties of the steady states. Sensitivity analysis shows that non-human primates and contaminated environments influence the dynamics of MVD in humans. The findings from numerical simulations indicate that shedding of Marburg virus from bats, monkeys, and humans plays a significant role in maintaining viral persistence. At the same time, the environment-to-human transmission remains a critical driver of the outbreak. Because direct control of non-human primates is ecologically infeasible, interventions should focus on accelerating environmental virus decay, reducing human exposure to contaminated sites, and strengthening infection prevention in healthcare set. These findings offer quantitative insights for developing targeted strategies to minimize MVD in the human population.
Compiled table of maize samples’ associated locations, mycotoxin concentrations, soil, and NDVI values from the 2019 survey.
(PLOS One, 2025-01-13) Stafstrom, William; Ngure, Francis; Mshanga, John; Wells, Henry; Nelson, Rebecca; Mischler, John
Compiled table of maize samples’ associated locations, mycotoxin concentrations, soil, and NDVI values from the 2019 survey.