Browsing Life sciences and Bio-engineering by Author "Makule, Edna"
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Acute and Subacute Oral Toxicity Evaluation of Commiphora Campestris Methanolic Stem Bark Extract (CASBMCE) In Mice and Rats
Chacha, Musa; Nyunza, Furaha; Makule, Edna (Juniper Publishers, 2017-11-16)This study was done to evaluate the acute and sub acute toxicity of Camiphora campestris Methanolic Stem Bark Extract (CASBMCE). In acute toxicity tests four groups of mice (n=5/group/sex) were orally treated with doses ... -
Cashew apple in Tanzania: status of utilization, challenges, and opportunities for sustainable development
Dimoso, Noel; Kassim, Neema; Makule, Edna (F1000 Research, 2022-11-21)Home Browse Cashew apple in Tanzania: status of utilization, challenges, and opportunities... ALL METRICS 143 VIEWS 14 DOWNLOADS Get PDF Get XML Cite Export Track Share ▬ POLICY BRIEF Cashew ... -
Challenges and opportunities toward sustainable consumption and value addition of cashew apples in Tanzania
Dimoso, Noel; Aluko, Angela; Makule, Edna; Kassim, Neema (SAGE Publications, 2020-07-31)Cashew apple is an important healthy fruit due to its high nutrient contents, particularly vitamin C. However, its full potential is yet to be realized in low technological countries. This paper explores farmers’ consumption ... -
Climate-smart aquaculture in Tanzania: Assessment of transitional and heavy metals concentrations in a commonly used local feed ingredient for Tilapia farming
Vulla, Kelvin; Mmanda, Francis; Makule, Edna (IJASRE, 2023-11)A study conducted from January through May 2023 to assess the concentrations of heavy and transitional metals in a commonly used local feed ingredient in a farmed Nile tilapia diet (Oreochromis niloticus) in Tanzania. ... -
Demography of baobab (Adansonia digitata L.) population in different land uses in the semi-arid areas of Tanzania
Msalilwa, Upendo; Ndakidem, Patrick; Makule, Edna; Munishi, Linus (Elsevier, 2020-12)Baobab is a deciduous non-timber tree species that are facing severe threats from both anthropogenic and climatic pressures across its range states. This study assessed natural rates of recruitment and associated threats ... -
Diarylheptanoid Glycosides of Morella salicifolia Bark
Makule, Edna; Schmidt, Thomas; Heilmann, Jörg; Kraus, Birgit (NM-AIST, 2017-12-19)A methanolic extract of Morella salicifolia bark was fractionated by various chromatographic techniques yielding six previously unknown cyclic diarylheptanoids, namely, 7-hydroxymyricanol 5-O-β-D-glucopyranoside (1), ... -
Dioic acid glycosides, tannins and methylated ellagic acid glycosides from Morella salicifolia bark
Makule, Edna; Krausa, Birgit; Jürgenliemka, Guido; Heilmanna, Jörg; Wiesnetha, Stefan (Elsevier Ltd., 2018)The bark of Morella salicifolia (HOCHST. EX A. RICH.) VERDC. & POLHILL (Myricaceae) is a common herbal drug and especially utilized by the Maasai community of northeastern Tanzania. It is traditionally used to treat ... -
Effect of clarification on physicochemical properties and nutrient retention of pressed and blended cashew apple juice
Aluko, Angela; Makule, Edna; Kassim, Neema (Wiley Online Library, 2023-01-11)The cashew apple is a nutritious pseudofruit of the cashew tree, after the nut. It is highly perishable and has an astringent taste, which hinder its utilization in the food sector. This study was designed to optimize ... -
Effect of processing on nutritional and anti-nutritional composition of false sesame (Ceratotheca sesamoides) and common bean leaves (Phaseolus vulgaris)
Kandonga, Agness; Makule, Edna; Matemu, Athanasia (International Journal of Biosciences, 2019-08-19)The effects of blanching and drying on micro-nutrients: β-Carotene, Vitamin C, Folic acid, Iron (Fe), Zinc (Zn), Phosphorus (P) and anti-nutrients: Tannins and Oxalates composition of False Sesame Leaves (FSL) and Common ... -
The effect of traditional and improved solar drying methods on the sensory quality and nutritional composition of fruits: A case of mangoes and pineapples
Mohammed, Ssemwanga; Makule, Edna; Siraj, Kayondo (Elsevier, 2020-06-17)Background This study investigated the effect of traditional and improved solar drying methods on the sensory quality and nutritional composition of the dried fruit products; using mangoes and pineapples, as a case study. ... -
Effectiveness and Suitability of Oyster Mushroom in Improving the Nutritional Value of Maize Flour Used in Complementary Foods
Siyame, Prisca; Kassim, Neema; Makule, Edna (Hindawi, 2021-03-16)Complementary foods based on habitual cereals such as maize have been linked with the promotion of undernutrition in young children. Blending the starchy-rich maize with nutritious-rich indigenous food such as oyster ... -
Effectiveness of complementary sorting methods in reducing aflatoxin contamination in groundnuts
Mshanga, John; Makule, Edna; Ngure, Francis (BRILL WAGENINGEN ACADEMIC, 2023-12-07)Aflatoxin contamination of staple foods remains a public health concern in many tropical and sub-tropical countries. In sub-Saharan Africa, groundnuts are a significant source of aflatoxin (AF) in vulnerable populations such ... -
Emerging issues and challenges associated with conservation of the African baobab (Adansonia digitata L.) in the semi-arid areas of Tanzania
Msalilwa, Upendo; Munishi, Linus; Makule, Edna; Ndakidemi, Patrick (International Network for Natural Sciences, 2019-11)The aim of this review is to discuss the emerging issues and challenges in baobab conservation based on the climate change, emerging challenges related to herbivory and human use such as emerging of new markets for baobab ... -
Ethical considerations in the design and conduct of a cluster-randomised mycotoxin mitigation trial in Tanzania
Phillips, Erica; Turner, Paul; Ngure, Francis; Kassim, Neema; Makule, Edna; Smith, Laura; Nelson, Rebecca; Stoltzfus, Rebecca (Wageningen Academic Publishers, 2022-01-24)Aflatoxins are fungal metabolites that commonly contaminate staple food crops in tropical regions. Acute aflatoxin consumption in very high concentration causes aflatoxicosis and acute liver failure, while chronic, moderate ... -
Ethical Considerations of the Trial to Establish a Causal Linkage Between Mycotoxin Exposure and Child Stunting
Phillips, Erica; Turner, Paul; Kassim, Neema; Makule, Edna; Nelson, Rebecca; Ngure, Francis; Smith, Laura; Stoltzfus, Rebecca (Elsevier, 2021-06-21)Objectives Aflatoxins are fungal metabolites that commonly contaminate staple crops in tropical regions. Aflatoxin is a carcinogen and consumption at high-levels can lead to acute liver failure and aflatoxicosis. Multiple ... -
Evaluation of a point-of-use device used for autoantibody analysis and its potential for following microcystin leucine-arginine exposure
Ma, Hui; Loscher, Christine; Parle-McDermott, Anne; Fitzgerald, Jenny; Meneely, Julie; Elliott, Christopher; Welten, Richard; Mchau, Geofrey; Makule, Edna; Machunda, Revocatus; Gong, Yun; Kimanya, Martin; Crawley, Aoife; Maguire, Ivan; Murphy, Caroline; Kennedy, Richard (Frontiers, 2024-02-09)Introduction: Globally, the need for measuring exposure to algal toxins has become urgent due to ever-increasing reports of contamination in sea and freshwater, in shellfish and fish stocks and in aerosols. Methods: To ... -
Fatty Acid Contents and Stability of Oyster Nut Oil (Telfairia pedata) Compared to Flaxseed and Sunflower Oil
Mwakasege, Emmanuel; Treydte, Anna; Hoeglinger, Otmar; Kassim, Neema; Makule, Edna (Hindawi, 2021-11-21)The selection of healthy fats for consumption is important. Linoleic acid (LA) (omega-6) and alpha-linolenic acid (ALA) (omega-3) are essential polyunsaturated fatty acids required for the maintenance of good health; ... -
Heavy metals and lambda-cyhalothrin levels in prawns, water and sediments along the Indian Coastline of Tanzania
Patiri, Gloria; Makule, Edna; Matemu, Athanasia (International Journal of Biosciences, 2019-04-30)Heavy metals and pesticide residues in prawns, water and sediments, and sources of contamination were determined. Prawns, sediments and water samples were collected from agricultural farms and estuarine, along the coastline ... -
Investigating the Optimal Treatment to Improve Cashew Apple Juice Quality and Shelf Life
Aluko, Angela; Kassim, Neema; Makule, Edna (Hindawi, 2023-09-06)An investigation was carried out to extend the shelf life of cashew apple juice (CAJ) by up to 90 days from its natural shelf life. CAJ was obtained by pressing apples. Then, extracted juice was clarified, pasteurized, and ... -
Opportunities and challenges for wholegrain staple foods in sub-Saharan Africa
Taylor, John; de Kock, Henriëtte; Makule, Edna; Adebowale, Olalekan; Hamaker, Bruce; Milani, Peiman (Elsevier, 2022-03)