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Now showing items 31-40 of 58
TB or not TB? Definitive determination of species within the Mycobacterium tuberculosis complex in unprocessed sputum from adults with presumed multidrug-resistant tuberculosis
(Wiley, 2021-06-09)
Objectives
Differences among Mycobacterium tuberculosis complex (MTC) species may predict drug resistance or treatment success. Thus, we optimised and deployed the genotype MTBC assay (gMTBC) to identify MTC to the ...
Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania
(Oxford University Press, 2022-04-21)
Background: Rifampicin- or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis complex (MTBC) strains
account for considerable morbidity and mortality globally. WGS-based prediction of drug resistance may guide
clinical ...
Comparison of cone bioassay estimates at two laboratories with different Anopheles mosquitoes for quality assurance of pyrethroid insecticide-treated nets
(Springer Nature., 2022-07-07)
ckground: Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is con ducted by measuring physiochemical parameters, but not bioefcacy against malaria mosquitoes. This study ...
Genome Scan for Variable Genes Involved in Environmental Adaptations of Nubian Ibex
(Springer Nature Switzerland AG., 2021-06-17)
The Nubian ibex (Capra nubiana) is a wild goat species that inhabits the Sahara and Arabian deserts and is adapted to extreme
ambient temperatures, intense solar radiation, and scarcity of food and water resources. To ...
Prevalence and Predictors of Antibiotic Prescriptions at Primary Healthcare Facilities in the Dodoma Region, Central Tanzania: A Retrospective, Cross-Sectional Study
(MDPI, 2022-07-31)
Background: Accelerated by the misuse or overuse of antibiotics, antibiotic resistance remains a global public health threat. We report the prevalence and predictors of antibiotic prescriptions in primary healthcare ...
Reservoir dynamics of rabies in south-east Tanzania and the roles of cross-species transmission and domestic dog vaccination
(John Wiley & Sons, Inc., 2021-08-21)
Understanding the role of different species in the transmission of multi-host pathogens, such as rabies virus, is vital for effective control strategies. Across most of sub-Saharan Africa domestic dogs Canis familiaris are ...
The focused quantitative EEG bio-marker in studying childhood atrophic encephalopathy
(Springer Nature Limited, 2022-08-04)
Although it is a normal involution process in advanced age, brain atrophy—also termed atrophic
encephalopathy—can also occur prematurely in childhood as a consequential efect of brain tissues
injury through trauma or ...
Prevalence and predictors of self-medication with antibiotics in selected urban and rural districts of the Dodoma region, Central Tanzania: a cross-sectional study
(Springer Nature., 2022-06-22)
Background: Antibiotic resistance is a global health threat driven partly by self-medication with antibiotics (SMA).
This study aims to assess the prevalence and predictors of SMA in selected rural and urban communities ...
Development, feasibility and potential effectiveness of community-based continuous mass dog vaccination delivery strategies: lessons for optimization and replication
(bioRxiv, 2022-03-13)
Objectives Dog vaccination can eliminate rabies, but annual delivery strategies do not sustain vaccination coverage between campaigns. We describe the development of a community-based continuous mass dog vaccination (CBC-MDV) ...
Impact of early diagnosis of impaired glucose regulation in tuberculosis: Comparison of clinical outcomes in people with tuberculosis in Tanzania
(John Wiley & Sons, Inc., 2022-08-04)
Objective
Diabetes mellitus (DM) has been known to compromise tuberculosis (TB) treatment outcomes. Association data are limited for early hyperglycaemia detection and TB treatment outcomes. Thus, we assessed treatment ...