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Integrating contact tracing and wholegenome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study
(eLife, 2023-05-23)
Background:
Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass ...
Correlating food and nutritional patterns with cancers in the pediatric oncology population at two specialized hospitals in Tanzania
(Springer nature, 2024-01-11)
Background
This study of nutritional patterns in relation to cancers among pediatric oncology population in Tanzania was motivated by the lack of up-to-date information about the nutritional practices, the controversy ...
Integrating contact tracing and whole- genome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study
(eLife Sciences Publications Ltd, 2023-05-25)
Background:
Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass ...
Cone Bioassays Provide Reproducible Bioefficacy Estimates with Different Anopheline Mosquitoes and Can Be Used for Quality Assurance of Pyrethroid Insecticide Treated Nets
(Research Square, 2022-01-24)
Background
Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is conducted by measuring physiochemical
parameters, but not bioecacy against malaria mosquitoes. The cone ...
Participation in mass dog vaccination campaigns in Tanzania: Benefits of community engagement
(Frontiers, 2022-10-13)
Background: Canine rabies causes about 59,000 human deaths each year globally but the disease can be eliminated by sustaining sufficient dog vaccination coverage over several consecutive years. A challenge to achieving ...
Integrating a community-based continuous mass dog vaccination delivery strategy into the veterinary system of Tanzania: A process evaluation using normalization process theory
(Elsevier, 2023-06-03)
Abstract: Sustained vaccination coverage of domestic dog populations can interrupt rabies transmission. How-
ever, challenges remain including low dog owner participation, high operational costs associated with ...
A prospective study of predictors of HIV viral load rebound in an HIV hyperendemic rural population of KwaZulu-Natal, South Africa
(Pan African Medical Journal, 2023-08-02)
Introduction: globally, up to one third of people living with HIV had unsuppressed viral loads in 2020, making it imperative to understand the various predictors of HIV viral load rebound (HVLR) in specific hyperendemic ...
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
(Elsevier, 2024-11-25)
Background
As set out in Sustainable Development Goal 3.3, the target date for ending the HIV epidemic as a public health threat is 2030. Therefore, there is a crucial need to evaluate current epidemiological trends and ...
Rifampicin Exposure in Tuberculosis Patients with Comorbidities in Sub-Saharan Africa: Prioritising Populations for Treatment—A Systematic Review and Meta-analysis
(Springer International Publishing, 2025-07-03)
Background and Objectives
Emerging evidence suggests that comorbidities like human immunodeficiency virus (HIV) infection, diabetes mellitus (DM), and malnutrition in tuberculosis (TB) patients can alter drug concentrations, ...