Browsing by Author "Chacha, Musa"
Now showing items 1-20 of 60
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Acute and sub-acute toxicity studies of chloroform extracts of cucumis metuliferus and lippia kituiensis in mice and rats model
(World Journal of Pharmaceutical Research, 2020)Objective: To evaluate the acute and sub-acute oral toxicity of Cucumis metuliferus and Lippia kituiensis leaf chloroform extracts in mice and rats model. Methods: Acute oral toxicity study of chloroform extracts of L. ... -
Acute and Subacute Oral Toxicity Evaluation of Commiphora Campestris Methanolic Stem Bark Extract (CASBMCE) In Mice and Rats
(Juniper Publishers, 2017-11-16)This study was done to evaluate the acute and sub acute toxicity of Camiphora campestris Methanolic Stem Bark Extract (CASBMCE). In acute toxicity tests four groups of mice (n=5/group/sex) were orally treated with doses ... -
Acute oral toxicity study of Mystroxylon aethiopicum root bark aqueous extract in albino mice
(Journal of Medicinal Plants Research, 2016-10-03)Acute oral toxicity of Mystroxylon aethiopicum root bark aqueous was evaluated in albino mice of either sex. In this study, five groups of mice were orally treated with doses of 1000, 2000, 3000, 4000 and 5000 mg/kg body ... -
Adequacy of micronutrient fortification in the mandatory fortified food vehicles in Tanzana
(Emerald Publishing Limited, 2020-08-24)Purpose This study aims to update the information on the current status of micronutrient fortification for iron, zinc, folic acid and vitamin A in mandatory fortified food vehicles such as cooking oil, wheat and maize ... -
Allelopathic Effects of Sphaeranthus suaveolens on Seed Germination and Seedling Growth of Phaseolus vulgaris and Oryza sativa
(Hindawi, 2021-02-15)Weeds with allelopathic effect have been reported to cause significant damage in agriculture particularly in smallholder farming systems. ,is study assessed the allelopathic effects of different concentrations of crude ... -
Analysis of phytochemical composition of Bersama abyssinica by gas chromatography – mass spectrometry
(Journal of Pharmacognosy and Phytochemistry, 2014)Bersama abyssinica has been reported to possess a varied range of therapeutical and pharmacological applications due to presence of bioactive compounds. The present study was carried out to determine the phytochemical ... -
Antibacterial and antifungal activities of selected wild mushrooms from Southern Highlands of Tanzania
(American Journal of Research Communication, 2014)The antibacterial and antifungal activities of crude extracts of Lactarius sp, Russula kivuensis, Amanita muscaria, Amanita phalloides, Lactarius gymnocarpoides and Lactarius densifolius (wild mushrooms) were evaluated ... -
Antifungal Effects against Phaeoisariopsis personata under Greenhouse Conditions and Phytochemical Analysis of Jatropha curcas Leaf Extracts
(International Journal of Agriculture and Biology, 2021-07-10)The study was conducted to test the antifungal efficacy of J. curcas leaf extracts against Phaeoisariopsis personata (causal pathogen for groundnut late leaf spot disease) under in vivo conditions, and to identify important ... -
Antimalarial activity of Cucumis metuliferus and Lippia kituiensis against Plasmodium berghei infection in mice
(Dovepress, 2018)Background: The search for new antimalarial drugs has become progressively urgent due to plasmodial resistance to most of the commercially available antimalarial drugs. As part of this effort, the study evaluated the ... -
Antimicrobial activities of against selected pathogenic fungi and bacteria strains.
(Taylor & Francis Online, 2019-12-19)and are dangerous pathogens causing fungal diseases. and developed resistance to fungicides such as fluconazole. Similarly, pathogenic bacteria have become resistant to antibiotcs such as methicillin. Thus, searching ... -
Antimicrobial and Cytotoxicity Activity of Clausena anisata, Acokanthera shemperii and Olea europaea Growing in Tanzania
(European Journal of Medicinal Plants, 2016-04-21)Aims: To evaluate antimicrobial and cytotoxicity activities of Clausena anisata, Acokanthera shemperii and Olea europaea against seven Gram negative bacteria and fungal species. Study Design: Bioassay of antimicrobial ... -
Bioaccumulation and distribution pattern of heavy metals in aquaculture systems found in Arusha and Morogoro regions of Tanzania
(Taylor & Francis Group, 2020-08-20)The assessment of the current distribution and concentrations of As, Pb, Hg, Cd, and Cr in farmed catfish and tilapia, fish feed, and pond sediment in Tanzania is important in order to establish the potential dietary ... -
Chemical composition of ethanolic extracts of some wild mushrooms from Tanzania and their medicinal potentials
(Begell House Inc., 2016)The ethanolic extracts of 5 edible and inedible wild mushrooms collected from the Southern Highlands of Tanzania were characterized by gas chromatography–mass spectrometry. A total of 75 chemical compounds were obtained, ... -
Computational analysis of Urolithin A as a potential compound for anti-inflammatory, antioxidant, and neurodegenerative pathways
(Elsevier, 2025-02-01)Urolithin A, an active precursor derived from the metabolism of ellagitanins in rats and humans, is known for its potential health benefits, including stimulating mitophagy and promoting muscular skeletal function. While ... -
Context-specific optimal dietary guidelines for managing cancer for hospitalized patients in Tanzania
(Emerald Publishing Limited, 2022-06-23)Purpose – The lack of food-based dietary guidelines for managing cancer among hospitalized patients has led to an increasing economic burden on the government and families in low- and middle-economy countries. There have ... -
Cytotoxicity activity of some wild mushroom species from Southern Highlands of Tanzania
(American Journal of Research Communication, 2014)The crude extracts from six wild mushroom species (Russula cellulata, Afrocantharellussymoensis, Lactarius sp, Lactarius denigricans, Russula kivuensis, Amanita muscaria and Amanita phalloides) collected from the Southern ... -
Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses
(Taylor & Francis Online, 2020-03-19)Objectives: Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, ... -
Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses.
(Taylor & Francis online, 2020-03-19)Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, particularly ... -
Development of Plant-Based Yoghurt Rich in Bioavailable Essential Nutrients and Bioactive Compounds from Ingredients Available in East Africa
(Enviro Research Publishers., 2022-03-25)The main aim of the present study was to formulate a convenient plant based yoghurt (PBY) with essential nutrients and bioactive compounds comparable to that of cow's milk using locally available ingredients in East ... -
Effect of lactic acid fermentation, boiling and soaking on selected nutrients and health promoting components of mango seed kernels
(International Journal of Biosciences, 2020-12)Mango seed kernels are considered as wastes although they are rich in essential nutrients and bioactive compounds for human health. Lack of commercial application (unlike oil seeds) presence of antinutrients, difficulty ...
