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Impact of early diagnosis of impaired glucose regulation in tuberculosis: Comparison of clinical outcomes in people with tuberculosis in Tanzania

Byashalira, Kenneth; Chamba, Nyasatu; Alkabab, Yosra; Mbelele, Peter; Mpolya, Emmanuel; Ntinginya, Nyanda; Shayo, PendoMartha; Ramaiya, Kaushik; Lillebaek, Troels; Heysell, Scott K; Mmbaga, Blandina; Bygbjerg, Ib; Mpagama, Stellah; Christensen, Dirk (John Wiley & Sons, Inc., 2022-08-04)

Objective Diabetes mellitus (DM) has been known to compromise tuberculosis (TB) treatment outcomes. Association data are limited for early hyperglycaemia detection and TB treatment outcomes. Thus, we assessed treatment ...

Development, feasibility and potential effectiveness of community-based continuous mass dog vaccination delivery strategies: lessons for optimization and replication

Duamor, Christian; Hampson, Katie; Lankester, Felix; Lugelo, Ahmed; Mpolya, Emmanuel; Kreppel, Katharina; Cleaveland, Sarah; Wyke, Sally (bioRxiv, 2022-03-13)

Objectives Dog vaccination can eliminate rabies, but annual delivery strategies do not sustain vaccination coverage between campaigns. We describe the development of a community-based continuous mass dog vaccination (CBC-MDV) ...

Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania

Mbelele, Peter; Utpatel, Christian; Sauli, Elingarami; Mpolya, Emmanuel; Mutayoba, Beatrice; Barilar, Ivan; Dreyer, Viola; Merker, Matthias; Sariko, Margaretha; Swema, Buliga; Mmbaga, Blandina; Gratz, Jean; Addo, Kennedy; Pletschette, Michel; Niemann, Stefan; Houpt, Eric; Mpagama, Stellah; Heysell, Scott (Oxford University Press, 2022-04-21)

Background: Rifampicin- or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis complex (MTBC) strains account for considerable morbidity and mortality globally. WGS-based prediction of drug resistance may guide clinical ...

Ki-67, p53 and BCL-2 Expressions and their Association with Clinical Histopathology of Breast Cancer among Women in Tanzania

Mansouri, Hidaya; Mnango, Leah; Magorosa, Erick; Sauli, Elingarami; Mpolya, Emmanuel (Scientific Reports, 2019-07-09)

This study associated Ki-67, p53, and BCL-2 markers with clinical histopathological (CH) features using currently available limited data on these markers in Tanzania. Retrospective chart review study was conducted among ...

Research Article Influence of Water Sanitation,and Hygiene Practices on Common Infections Under-five Children in Longido and Monduli Districts of Arusha Tanzania

Mshida, Hoyce; Kassim, Neema; Kimanya, Martin; Mpolya, Emmanuel (Journal of Environmental and Public Health, 2017-09-25)

The study aimed at assessing water, sanitation, and hygiene practices and their influence on infectious diseases among underfive children in semipastoral communities of Arusha. The study was cross-sectional in design. ...

Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.

Kimanya, Martin; Routledge, Michael; Ezekiel, Chibundu; Shirima, Candida; Gong, Yun; Mpolya, Emmanuel (PLOS ONE, 2021-03-11)

Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced ...

Intestinal Schistosomiasis among Primary Schoolchildren in Two On-Shore Communities in Rorya District, Northwestern Tanzania: Prevalence, Intensity of Infection and Associated Risk Factors

Munisi, David; Buza, Joram; Mpolya, Emmanuel; Kinung’hi, Safari (Hindawi Publishing Corporation, 2016-09-15)

In Tanzania, Schistosoma mansoni is of great public health importance. Understanding the prevalence and infection intensity is important for targeted, evidence-based control strategies.This study aimed at studying the ...

Influence of Water, Sanitation, and Hygiene Practices on Common Infections among Under-Five Children in Longido and Monduli Districts of Arusha, Tanzania.

Mshida, Hoyce; Kassim, Neema; Kimanya, Martin; Mpolya, Emmanuel (Hindawi, 2017-09-25)

The study aimed at assessing water, sanitation, and hygiene practices and their influence on infectious diseases among under-five children in semipastoral communities of Arusha. The study was cross-sectional in design. ...

Schistosoma mansoni Infections, Undernutrition and Anaemia among Primary Schoolchildren in Two Onshore Villages in Rorya District, North-Western Tanzania

Munisi, David; Buza, Joram; Mpolya, Emmanuel; Kinung'hi, Safari (Plos One, 2016-12-09)

Background Undernutrition and anaemia remains to be a major public health problem in many developing countries, where they mostly affect children. Intestinal parasitic infections are known to affect both growth and ...

Pattern and Distribution of Colorectal Cancer in Tanzania: A Retrospective Chart Audit at Two National Hospitals

Katalambula, Leonard; Ntwenya, Julius; Ngoma, Twalib; Buza, Joram; Mpolya, Emmanuel; Mtumwa, Abdallah; Petrucka, Pammla (Hindawi Publishing Corporation, 2016-08-09)

Background. Colorectal cancer (CRC) is a growing public health concern with increasing rates in countries with previously known low incidence. This study determined pattern and distribution of CRC in Tanzania and identified ...