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Kiwira Virus, a Newfound Hantavirus Discovered in Free-Tailed Bats (Molossidae) in East and Central Africa
(MDPI, 2022-10-27)
A novel hantavirus, named Kiwira virus, was molecularly detected in six Angolan free-
tailed bats (Mops condylurus, family Molossidae) captured in Tanzania and in one free-tailed bat in the
Democratic Republic of Congo. ...
Taenia multiceps in Northern Tanzania: An Important but Preventable Disease Problem in Pastoral and Agropastoral Farming Systems
(MDPI, 2022-08-26)
Coenurosis due to Taenia multiceps has emerged as a major concern to small ruminant-owning communities in northern Tanzania. Although a high incidence of disease has been reported, gaps still remain in our knowledge of the ...
Latent class evaluation of the performance of serological tests for exposure to Brucella spp. in cattle, sheep, and goats in Tanzania
(PLOS Medicine, 2021-08-24)
Brucellosis is a neglected zoonosis endemic in many countries, including regions of sub-Saharan Africa. Evaluated diagnostic tools for the detection of exposure to Brucella spp. are important for disease surveillance and ...
Conjugative Plasmids Disseminating CTX-M-15 among Human, Animals and the Environment in Mwanza Tanzania: A Need to Intensify One Health Approach
(MDPI, 2021-07-09)
Background: Globally, blaCTX-M-15 beta-lactamases are the most popular extended spectrum beta-lactamase alleles that are widely distributed due its mobilisation by mobile genetic elements in several compartments. We aimed ...
Antimicrobial resistant coliforms across four poultry production systems in Arusha and Moshi, Tanzania
(Pan African Medical Journal, 2022-01-11)
Introduction: resistance to antimicrobials poses a
threat to human and animal health. This study
aimed to determine the prevalence of resistant
coliforms in poultry cloacal samples collected from
different poultry ...
Combining Multiple Assays Improves Detection and Serotyping of Foot-and-Mouth Disease Virus. A Practical Example with Field Samples from East Africa
(MDPI, 2021-08-10)
Multiple serotypes and topotypes of foot-and-mouth disease virus (FMDV) circulate in endemic areas, posing considerable impacts locally. In addition, introductions into new areas are of great concern. Indeed, in recent ...
Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Inc., 2021-02-23)
The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug ...
Solvent effects on host-guest residence time and kinetics: further insights from metadynamics simulation of Toussaintine-A unbiding from chitosan nanoparticle
(Springer Nature, 2021-04-14)
Solvents play an important role in host-guest intermolecular interactions. The kinetics and residence time of Toussaintine-A (TouA) unbinding from chitosan was investigated by means of well-tempered metadynamics and ...
Performance characteristics and costs of serological tests for brucellosis in a pastoralist community of northern Tanzania
(Springer Nature Limited, 2021-03-09)
The control of brucellosis across sub-Saharan Africa is hampered by the lack of standardized testing and the use of tests with poor performance. This study evaluated the performance and costs of serological assays for human ...
Diagnosis Challenges and Control Strategies of Transboundary Diseases Presenting with Respiratory Signs in Small Ruminants in Developing Countries: Emphasis on Contagious Caprine Pleuropneumonia and Peste Des Petits Ruminants
(International Journal of TROPICAL DISEASE & Health, 2020-12-31)
Aims: To review the diagnosis challenges and control strategies of the diseases presenting with respiratory signs. The emphasis being more on two transboundary animal diseases of small ruminants; contagious caprine ...