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Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice
(Dovepress, 2015-02-20)
: Tafenoquine (TQ), a new synthetic analog of primaquine, has relatively poor
bioavailability and associated toxicity in glucose-6-phosphate dehydrogenase (G6PD)-deficient
individuals. A microemulsion formulation of TQ ...
Human food safety and environmental hazards associated with the use of methyltestosterone and other steroids in production of all-male tilapia
(Springer, 2015-04)
In recent years, all-male cultures of Nile tilapia (Oreochromis niloticus) have been the most preferred mode of production in aquaculture industry. All-male individuals achieve higher somatic growth rate and shut high ...
Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities
(Springer, 2015-03-28)
Purpose There is significant interest in the application of nanoparticles
to deliver immunostimulatory signals to cells.We hypothesized
that curdlan (immune stimulating polymer) could be conjugated
to PLGA and nanoparticles ...
Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis
(Elsevier, 2015-06-06)
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development
of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
Nanomedicine: Past, present and future - A global perspective.
(Elsevier Inc, 2015-12-18)
Nanomedicine is an emerging and rapidly evolving field and includes the use of nanoparticles for diagnosis and therapy of a variety of diseases, as well as in regenerative medicine. In this mini-review, leaders in the field ...