Browsing Life sciences and Bio-engineering by Author "Seth, Misago"
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Challenges in Diagnosis of Febrile illnesses in Tanzania in the Era of Declining Malaria Epidemiology
Seth, Misago; Mdetele, Daniel; Phillips, Scott; Buza, Joram (American Journal of Research Communication, 2015)Malaria and other febrile illnesses are very common especially in children in developing countries. Due to reliance on clinical algorithms for diagnosis in resource-poor settings, most febrile episodes have always been ... -
Designing and development of multiplex rapid diagnostic test platforms for health-related point-of-care applications in the developing world
Seth, Misago (NM-AIST, 2019-04)Accurate and timely diagnosis is usually an important step towards appropriate disease management. In resource-limited settings, healthcare workers lack proper facilities to perform vital tests, and the diagnosis of disease ... -
Immunochromatographic thread-based test platform for diagnosis of infectious diseases
Seth, Misago; Mdetele, Daniel; Buza, Joram (Springer Nature Switzerland AG., 2018-03-31)Patterning is an important step in fabrication of multiplexed microfluidic devices. Various approaches including cutting, photolithography, wax-printing, plotting and etching have been developed and tested. Recently, using ... -
Multiplex paper-based designs for point-of-care (POC) diagnostics
Seth, Misago; Buza, Joram (International Journal of Research in Medical Sciences, 2018-11)Background: Accurate and timely diagnosis is usually the first step towards appropriate disease management. In resource-limited settings, healthcare workers lack proper facilities to perform vital tests, and the diagnosis ... -
Potential Opportunities and Challenges of Deploying Next Generation Sequencing and CRISPR-Cas Systems to Support Diagnostics and Surveillance Towards Malaria Control and Elimination in Africa
Lyimo, Beatus; Popkin-Hall, Zachary; Giesbrecht, David; Mandara, Celine; Madebe, Rashid; Bakari, Catherine; Pereus, Dativa; Seth, Misago; Ngamba, Ramadhan; Mbwambo, Ruth; MacInnis, Bronwyn; Mbwambo, Daniel; Garimo, Issa; Chacky, Frank; Aaron, Sijenunu; Lusasi, Abdallah; Molteni, Fabrizio; Njau, Ritha; Cunningham, Jane; Lazaro, Samwel; Mohamed, Ally; Juliano, Jonathan; Bailey, Jeffrey; Ishengoma, Deus (Frontiers, 2022-07-13)Recent developments in molecular biology and genomics have revolutionized biology and medicine mainly in the developed world. The application of next generation sequencing (NGS) and CRISPR-Cas tools is now poised to support ...