Research Articles [LISBE]: Recent submissions
Now showing items 221-240 of 886
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Performance characteristics and costs of serological tests for brucellosis in a pastoralist community of northern Tanzania
(Springer Nature Limited, 2021-03-09)The control of brucellosis across sub-Saharan Africa is hampered by the lack of standardized testing and the use of tests with poor performance. This study evaluated the performance and costs of serological assays for human ... -
Enhancing livestock vaccination decision-making through rapid diagnostic testing
(Elsevier Ltd., 2019-12)• Compared to vaccination, the collective approach to diagnostic testing presents a low-fixed cost. • Existing household livestock-health behaviors increase the likelihood for uptake of preventative health practices. ... -
Molecular epidemiology of Brucella species in mixed livestock-human ecosystems in Kenya
(Springer Nature Limited, 2021-04-23)Brucellosis, caused by several species of the genus Brucella, is a zoonotic disease that affects humans and animal species worldwide. Information on the Brucella species circulating in different hosts in Kenya is largely ... -
Conjugative Plasmids Disseminating CTX-M-15 among Human, Animals and the Environment in Mwanza Tanzania: A Need to Intensify One Health Approach
(MDPI, 2021-07-09)Background: Globally, blaCTX-M-15 beta-lactamases are the most popular extended spectrum beta-lactamase alleles that are widely distributed due its mobilisation by mobile genetic elements in several compartments. We aimed ... -
How can we realise the full potential of animal health systems for delivering development and health outcomes?
(Europe PMC, 2021-08-21)Animal health services play an essential role in supporting livestock production, with the potential to address the challenges of hunger, poverty, health, social justice and environmental health as part of the path towards ... -
Combining Multiple Assays Improves Detection and Serotyping of Foot-and-Mouth Disease Virus. A Practical Example with Field Samples from East Africa
(MDPI, 2021-08-10)Multiple serotypes and topotypes of foot-and-mouth disease virus (FMDV) circulate in endemic areas, posing considerable impacts locally. In addition, introductions into new areas are of great concern. Indeed, in recent ... -
A Monitoring System for Transboundary Foot and Mouth Disease (FMD) considering the Demographic Characteristics in Gairo, Tanzania
(Engineering, Technology & Applied Science Research (ETASR), 2021-08)-Foot and Mouth Disease (FMD) is present in many countries, including Tanzania. Gairo is among the districts that frequently face FMD. This study found that the current mechanism for communicating FMD in Gairo district ... -
Latent class evaluation of the performance of serological tests for exposure to Brucella spp. in cattle, sheep, and goats in Tanzania
(PLOS Medicine, 2021-08-24)Brucellosis is a neglected zoonosis endemic in many countries, including regions of sub-Saharan Africa. Evaluated diagnostic tools for the detection of exposure to Brucella spp. are important for disease surveillance and ... -
How public health crises expose systemic, day-to-day health inequalities in low- and-middle income countries: an example from East Africa
(Springer Nature, 2022-02-14)Background: The current Coronavirus disease pandemic reveals political and structural inequities of the world’s poorest people who have little or no access to health care and yet the largest burdens of poor health. This ... -
Participatory mapping identifies risk areas and environmental predictors of endemic anthrax in rural Africa
(Springer Nature Limited, 2022-06-12)Disease mapping reveals geographical variability in incidence, which can help to prioritise control efforts. However, in areas where this is most needed, resources to generate the required data are often lacking. ... -
Multiple Pathogens Contribute to Human Immunodeficiency Virus-Related Sepsis in Addition to Mycobacterium tuberculosis: A Prospective Cohort in Tanzania
(PubMed Central, 2022-10-20)Background: Mortality from tuberculosis (TB) sepsis is common among patients living with human immunodeficiency virus (PLHIV). We aimed to detect M. tuberculosis (MTB) and additional sepsis etiologies, and mortality ... -
Epidemiology of leptospirosis in Tanzania: A review of the current status, serogroup diversity and reservoirs
(PLOS, 2021-11-16)Background Tanzania is among the tropical countries of Sub-Saharan Africa with the environmental conditions favorable for transmission of Leptospira. Leptospirosis is a neglected zoonotic disease, and although there are ... -
Antimicrobial resistant coliforms across four poultry production systems in Arusha and Moshi, Tanzania
(Pan African Medical Journal, 2022-01-11)Introduction: resistance to antimicrobials poses a threat to human and animal health. This study aimed to determine the prevalence of resistant coliforms in poultry cloacal samples collected from different poultry ... -
Taenia multiceps in Northern Tanzania: An Important but Preventable Disease Problem in Pastoral and Agropastoral Farming Systems
(MDPI, 2022-08-26)Coenurosis due to Taenia multiceps has emerged as a major concern to small ruminant-owning communities in northern Tanzania. Although a high incidence of disease has been reported, gaps still remain in our knowledge of the ... -
Kiwira Virus, a Newfound Hantavirus Discovered in Free-Tailed Bats (Molossidae) in East and Central Africa
(MDPI, 2022-10-27)A novel hantavirus, named Kiwira virus, was molecularly detected in six Angolan free- tailed bats (Mops condylurus, family Molossidae) captured in Tanzania and in one free-tailed bat in the Democratic Republic of Congo. ... -
Comparative analysis of clinical breakpoints, normalized resistance interpretation and epidemiological cut-offs in interpreting antimicrobial resistance of Escherichia coli isolates originating from poultry in different farm types in Tanzania
(Microbiology Society, 2014-07-14)Introduction. Existing breakpoint guidelines are not optimal for interpreting antimicrobial resistance (AMR) data from animal studies and low-income countries, and therefore their utility for analysing such data is limited. ... -
Acute and sub-acute toxicity studies of chloroform extracts of cucumis metuliferus and lippia kituiensis in mice and rats model
(World Journal of Pharmaceutical Research, 2020)Objective: To evaluate the acute and sub-acute oral toxicity of Cucumis metuliferus and Lippia kituiensis leaf chloroform extracts in mice and rats model. Methods: Acute oral toxicity study of chloroform extracts of L. ... -
Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses
(Taylor & Francis Online, 2020-03-19)Objectives: Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, ... -
Solvent effects on host-guest residence time and kinetics: further insights from metadynamics simulation of Toussaintine-A unbiding from chitosan nanoparticle
(Springer Nature, 2021-04-14)Solvents play an important role in host-guest intermolecular interactions. The kinetics and residence time of Toussaintine-A (TouA) unbinding from chitosan was investigated by means of well-tempered metadynamics and ... -
Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Inc., 2021-02-23)The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug ...
