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Modeling the proteome of a Marek's disease transformed cell line: a natural animal model for CD30 overexpressing lymphomas.
(Proteomics, 2007-04-18)
Marek's disease (MD) in the chicken, caused by the highly infectious MD alpha-herpesvirus (MDV), is both commercially important and a unique, naturally occurring model for human T-cell lymphomas overexpressing the Hodgkin's ...
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands
(Elsevier, 2008)
Single-stranded viral RNA (ssRNA) was recently identified as the natural ligand for TLR7
and TLR8. ssRNA sequences from viruses, as well as their synthetic analogues stimulate
innate immune responses in immune cells from ...
The neoplastically transformed (CD30hi) Marek’s disease lymphoma cell phenotype most closely resembles T-regulatory cells
(Springer-Verlag, 2008-02-07)
Introduction Marek’s disease (MD), a herpesvirus-induced
lymphoma of chickens is a unique natural model of CD30-
overexpressing (CD30hi) lymphoma. We have previously
proposed that the CD30hi neoplastically transformed ...
Genotype-Dependent Tumor Regression in Marek’s Disease Mediated at the Level of Tumor Immunity
(Springer, 2008-03-18)
Marek’s disease (MD) of chickens is a unique
natural model of Hodgkin’s and Non Hodgkin’s lymphomas
in which the neoplastically-transformed cells over-express
CD30 (CD30hi) antigen. All chicken genotypes can be
infected ...
Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
(Blackwell Science Ltd, 2003)
The first visible response in livestock to the bite of a trypanosomeinfected
tsetse fly is the formation of a localized skin reaction,
also known as a chancre. This is an inflammatory response in
the skin associated ...