Browsing Research Articles [LISBE] by Author "Naidoo, Saloshnee"
Now showing items 1-3 of 3
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Design and formulation of nano-sized spray dried efavirenz-part I: influence of formulation parameters
Katata, Lebogang; Tshweu, Lesego; Naidoo, Saloshnee; Kalombo, Lonji; Swai, Hulda (Springer Nature Switzerland AG., 2012-10-25)Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 μg/mL), which leads to a ... -
Preparation of rifampicin/poly(d,l-lactice) nanoparticles for sustained release by supercritical assisted atomization technique
Labuschagne, Philip; Adami, Renata; Liparoti, Sara; Naidoo, Saloshnee; Reverchon, E.; Swai, Hulda (Elsevier, 2014-11)In this work supercritical assisted atomization (SAA) process was used for the co-precipitation of poly(d,l-lactide) (PDLLA) and rifampicin (RIF) as nanoparticles for sustained release applications. The effect of the ... -
Spray-Dried, Nanoencapsulated, Multi-Drug Anti-Tuberculosis Therapy Aimed at OnceWeekly Administration for the Duration of Treatment
Kalombo, Lonji; Lemmer, Yolandy; Semete-Makokotlela, Boitumelo; Ramalapa, Bathabile; Nkuna, Patric; Booysen, Laetitia; Naidoo, Saloshnee; Hayeshi, Rose; Verschoor, Jan; Swai, Hulda (MDPI, 2019-08-15)Aiming to improve the treatment outcomes of current daily tuberculosis (TB) chemotherapy over several months, we investigated whether nanoencapsulation of existing drugs would allow decreasing the treatment frequency to ...