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dc.contributor.authorAndrianaivoarimanana, Voahangy
dc.contributor.authorKreppel, Katharina
dc.contributor.authorElissa, Nohal
dc.contributor.authorDuplantier, Jean-Marc
dc.contributor.authorCarniel, Elisabeth
dc.contributor.authorRajerison, Minoarisoa
dc.contributor.authorJambou, Ronan
dc.date.accessioned2020-01-23T09:34:40Z
dc.date.available2020-01-23T09:34:40Z
dc.date.issued2013-11-01
dc.identifier.other24244760
dc.identifier.uridoi: 10.1371/journal.pntd.0002382
dc.identifier.urihttp://dspace.nm-aist.ac.tz/handle/123456789/535
dc.descriptionResearch Article published by PLOS Neglected Tropical Diseases, Volume 7, Issue 11, November 2013en_US
dc.description.abstractPlague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar.en_US
dc.language.isoenen_US
dc.publisherPLOS Neglected Tropical Diseasesen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titleUnderstanding the persistence of plague foci in Madagascar.en_US
dc.typeArticleen_US


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