Browsing Materials, Energy, Water and Environmental Sciences by Author "Ntie-Kang, Fidele"
Now showing items 1-2 of 2
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A computer-based approach for developing linamarase inhibitory agents
Paul, Lucas; Mudogo, Celestin; Mtei, Kelvin; Machunda, Revocatus; Ntie-Kang, Fidele (Walter de Gruyter GmbH, 2020-04-18)Cassava is a strategic crop, especially for developing countries. However, the presence of cyanogenic compounds in cassava products limits the proper nutrients utilization. Due to the poor availability of structure discovery ... -
Structural characterization of cassava linamarase-linamarin enzyme complex: an integrated computational approach
Lucas, Paul; Shadrack, DM; Mudogo, CN; Mtei, KM; Machunda, RL; Ntie-Kang, Fidele (Journal of Biomolecular Structure and Dynamics, 2022)Cassava linamarase is a hydrolyzing enzyme that belongs to a glycoside hydrolase family 1 (GH1). It is responsible for breaking down linamarin to toxic cyanide. The enzyme provides a defensive mechanism for plants against ...