Polyphosphates: Essential bioenergetic reservoirs and their role as critical nutrient depleters in biological systems
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Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
Scientific Research Archives
Abstract
Polyphosphates are linear polymers of inorganic phosphate that play a pivotal role in cellular bioenergetics and
metabolism across a wide range of organisms. This review article explores the multifaceted functions of polyphosphates
as essential bioenergetic reservoirs, highlighting their ability to store and release energy, thereby facilitating various
biochemical processes. We discuss the synthesis and degradation pathways of polyphosphates, their influence on ATP
metabolism, and their regulatory roles in cellular signaling and stress responses. Additionally, we examine how
polyphosphates act as critical nutrient depleters in biological systems, impacting phosphate homeostasis. The interplay
between polyphosphate metabolism and nutrient availability is scrutinized, with implications for microbial ecology,
agricultural practices, and biotechnological applications. By integrating current research findings, this review
emphasizes the significance of polyphosphates not only as energy reservoirs but also as key players in nutrient cycling
and environmental sustainability, underscoring their importance in both basic and applied biological sciences.
Sustainable Development Goals
SDG 2: Zero Hunger
SDG 12: Responsible Consumption and Production
SDG 6: Clean Water and Sanitation
Keywords
Polyphosphate, Bioenergetics, Adenosine Triphosphate, Nutrient depleters