Show simple item record

dc.contributor.authorLankester, Felix
dc.contributor.authorKibona, Tito
dc.contributor.authorAllan, Kathryn
dc.contributor.authorGlanville, William
dc.contributor.authorBuza, Joram
dc.contributor.authorKatzer, Frank
dc.contributor.authorMmbaga, Blandina
dc.contributor.authorWheelhouse, Nick
dc.contributor.authorInnes, Elisabeth
dc.contributor.authorThomas, Kate
dc.contributor.authorNyasebwa, Obed
dc.contributor.authorSwai, Emanuel
dc.contributor.authorClaxton, John
dc.contributor.authorCleaveland, Sarah
dc.date.accessioned2025-01-20T08:20:53Z
dc.date.available2025-01-20T08:20:53Z
dc.date.issued2024-12-16
dc.identifier.urihttps://doi.org/10.7554/eLife.95296
dc.identifier.urihttps://dspace.nm-aist.ac.tz/handle/20.500.12479/2863
dc.descriptionThis research article was published by Epidemiology and Global Health | Microbiology and Infectious Disease, 2024en_US
dc.description.abstractLack of data on the aetiology of livestock diseases constrains effective interventions to improve livelihoods, food security and public health. Livestock abortion is an important disease syndrome affecting productivity and public health. Several pathogens are associated with livestock abortions but across Africa surveillance data rarely include information from abortions, little is known about aetiology and impacts, and data are not available to inform interventions. This paper describes outcomes from a surveillance platform established in Tanzania spanning pastoral, agropastoral and smallholder systems to investigate causes and impacts of livestock abortion. Abortion events were reported by farmers to livestock field officers (LFO) and on to investigation teams. Events were included if the research team or LFO could attend within 72 hr. If so, samples and questionnaire data were collected to investigate (a) determinants of attribution; (b) patterns of events, including species and breed, previous abortion history, and seasonality; (c) determinants of reporting, investigation and attribution; (d) cases involving zoonotic pathogens. Between 2017–2019, 215 events in cattle (n=71), sheep (n=44), and goats (n=100) were investigated. Attribution, achieved for 19.5% of cases, was significantly affected by delays in obtaining samples. Histopathology proved less useful than PCR due to rapid deterioration of samples. Vaginal swabs provided practical and sensitive material for pathogen detection. Livestock abortion surveillance, even at a small scale, can generate valuable information on causes of disease outbreaks, reproductive losses and can identify pathogens not easily captured through other forms of livestock disease surveillance. This study demonstrated the feasibility of establishing a surveillance system, achieved through engagement of community-based field officers, establishment of practical sample collection and application of molecular diagnostic platforms.en_US
dc.language.isoenen_US
dc.publishereLife Sciences Publications Limiteden_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titleLivestock abortion surveillance in Tanzania reveals disease priorities and importance of timely collection of vaginal swab samples for attributionen_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record