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CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands

Buza, Joram; Benjamin, Ponn; Zhu, Jianzhung; Wilson, Heather; Lipford, Grayson; Krieg, Arthur; Babiuk, Lorne; Mutwiri, George (Elsevier, 2008)

Single-stranded viral RNA (ssRNA) was recently identified as the natural ligand for TLR7 and TLR8. ssRNA sequences from viruses, as well as their synthetic analogues stimulate innate immune responses in immune cells from ...