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Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration
(Elsevier B.V., 2012-03-15)
The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ...
Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice
(Dovepress, 2015-02-20)
: Tafenoquine (TQ), a new synthetic analog of primaquine, has relatively poor
bioavailability and associated toxicity in glucose-6-phosphate dehydrogenase (G6PD)-deficient
individuals. A microemulsion formulation of TQ ...
Effects of spray-drying on w/o/w multiple emulsions prepared from a stearic acid matrix
(2014-01-01)
The goal of this study was to explore the effects of spray-drying on w/o/w double emulsions of methyltestosterone (MT) loaded in a stearic acid matrix. MT-loaded nanoparticles were formulated by a water-in-oil-in-water ...
Antimicrobial dependence of silver nanoparticles on surface plasmon resonance bands against Escherichia coli
(Dove Press Journal, 2016-12-16)
This study presents a simple and trouble-free method for determining the antimicrobial
properties of silver nanoparticles (AgNPs) based on the surface plasmon resonance
(SPR) bands. AgNPs were prepared by chemical reduction ...
Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses.
(Taylor & Francis online, 2020-03-19)
Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, particularly ...
Optimized Preparation of Silver Nanoparticles from Polyethylene Glycol and Formaldehyde
(International Research Journal of Pure & Applied Chemistry, 2016-12-19)
The purpose of this work was to study the effect of various process and formulation parameters on
size and shapes of silver nanoparticles (AgNPs) based on surface plasmon resonance (SPR).
AgNPs were prepared by chemical ...
Antimicrobial packaging based on starch, poly(3-hydroxybutyrate) and poly(lactic-co-glycolide) materials and application challenges
(Elsevier Ltd., 2018-04)
Background
In recent years, food packaging has focused on two scientific pillars; adopting the biodegradable packaging materials and development of antimicrobial packaging for extended shelf life, quality and safety of ...
Standardization of natural mycolic acid antigen composition and production for use in biomarker antibody detection to diagnose active tuberculosis
(Elsevier B.V., 2016-08)
Mycobacterium tuberculosis, the causative agent of tuberculosis, is characterized by the abundance of species specific, antigenic cell wall lipids called mycolic acids. These wax-like molecules all share an identical, ...
Poly (D,L-lactide-co-glycolide) nanoparticles: Uptake by epithelial cells and cytotoxicity
(eXPRESS Polymer Letters, 2014)
Nanoparticles as drug delivery systems offer benefits such as protection of the encapsulated drug against degradation, site-specific targeting and prolonged blood circulation times. The aim of this study was to investigate ...
Design and formulation of nano-sized spray dried efavirenz-part I: influence of formulation parameters
(Springer Nature Switzerland AG., 2012-10-25)
Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 μg/mL), which leads to a ...