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Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration

Semete, Boitumelo; Booysen, Laetitia; Kalombo, Lonji; Ramalapa, Bathabile; Hayeshi, Rose; Swai, Hulda (Elsevier B.V., 2012-03-15)

The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ...

Exercise-dependent regulation of glial cell line-derived neurotrophic factor (GDNF) expression in skeletal muscle and its importance for the neuromuscular system

Vianney, John-Mary; McCullough, Monica J.; Gyorkos, Amy M.; Spitsbergen, John M. (Higher Education Press and Springer-Verlag Berlin Heidelberg, 2012)

The focus of this review is to highlight the importance of glial cell line-derived neurotrophic factor (GDNF) for the motor nervous system. GDNF is the most potent survival factor for motor neurons, where it enhances maintenance ...

Resistance of Bacillus cereus and its enterotoxin genes in ready-to-eat foods to γ-irradiation

Mtenga, Adelard B.; Kassim, Neema; Lee, Won-Gyeong; Shim, Won-Bo; Yoon, Yohan; Chung, Duck-Hwa (Springer Nature Switzerland AG., 2012-04-30)

This study was investigated the resistance of Bacillus cereus ATCC 13752 and its enterotoxin coding genes in cereals, vegetables, and tryptic soy broth to γ-irradiation. Screening for enterotoxin coding genes, viability ...

Design and formulation of nano-sized spray dried efavirenz-part I: influence of formulation parameters

Katata, Lebogang; Tshweu, Lesego; Naidoo, Saloshnee; Kalombo, Lonji; Swai, Hulda (Springer Nature Switzerland AG., 2012-10-25)

Efavirenz (EFV) is one of the first-line antiretroviral drugs recommended by the World Health Organisation for treating HIV. It is a hydrophobic drug that suffers from low aqueous solubility (4 μg/mL), which leads to a ...

Porous Polyethylene Composite as Biomass Carrier for Red Pigment Production Using Monosodium Glutamate Wastewater as Medium

Li, Xiaolong; Zhang, Fengqin; Li, Taotao; Lu, Zhuoxuan; Zhang, Liming; Sauli, Elingarami; He, Nongyue (American Scientific Publishers, 2012-10-01)

Abundant acidic wastewater from monosodium glutamate production is difficult to treat, leading to serious water pollution. Utilization of monosodium glutamate wastewater (MSGW) with high concentration of COD (33170 mg/L) ...

The effect of plant extracts as seed treatments to control bacterial leaf spot of tomato in Tanzania

Mbega, Ernest; Mortensen, Carmen; Mabagala, Robert; Wulff, Ednar (Springer Nature, 2012-05-05)

Bacterial leaf spot (BLS) caused by seed-borne xanthomonads is a serious disease of tomato (Solanum lycopersicum L.), causing significant losses in both yield and quality. To identify more effective control measures, we ...

Nuclear Factor kappa B is central to Marek’s Disease herpesvirus induced neoplastic transformation of CD30 expressing lymphocytes in-vivo

Kumar, Shyamesh; Kunec, Dusan; Buza, Joram; Chiang, Hsin-I; Zhou, Huaijun; Subramaniam, Sugalesini; Pendarvis, Ken (BMC Systems Biology, 2012)

Background: Marek’s Disease (MD) is a hyperproliferative, lymphomatous, neoplastic disease of chickens caused by the oncogenic Gallid herpesvirus type 2 (GaHV-2; MDV). Like several human lymphomas the neoplastic MD lymphoma ...