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Impact of early diagnosis of impaired glucose regulation in tuberculosis: Comparison of clinical outcomes in people with tuberculosis in Tanzania
(John Wiley & Sons, Inc., 2022-08-04)
Objective
Diabetes mellitus (DM) has been known to compromise tuberculosis (TB) treatment outcomes. Association data are limited for early hyperglycaemia detection and TB treatment outcomes. Thus, we assessed treatment ...
Development, feasibility and potential effectiveness of community-based continuous mass dog vaccination delivery strategies: lessons for optimization and replication
(bioRxiv, 2022-03-13)
Objectives Dog vaccination can eliminate rabies, but annual delivery strategies do not sustain vaccination coverage between campaigns. We describe the development of a community-based continuous mass dog vaccination (CBC-MDV) ...
Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania
(Oxford University Press, 2022-04-21)
Background: Rifampicin- or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis complex (MTBC) strains
account for considerable morbidity and mortality globally. WGS-based prediction of drug resistance may guide
clinical ...
Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.
(PLOS ONE, 2021-03-11)
Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced ...
A case-control study on the driving factors of childhood brain volume loss: What pediatricians must explore
(PLOS ONE, 2022-12-30)
Background
The brain volume loss also known as brain atrophy is increasingly observed among children in the course of performing neuroimaging using CT scan and MRI brains. While severe forms of brain volume loss are ...
Participation in mass dog vaccination campaigns in Tanzania: Benefits of community engagement
(Frontiers, 2022-10-13)
Background: Canine rabies causes about 59,000 human deaths each year globally but the disease can be eliminated by sustaining sufficient dog vaccination coverage over several consecutive years. A challenge to achieving ...
Integrating contact tracing and wholegenome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study
(eLife, 2023-05-23)
Background:
Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass ...