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Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis
(Elsevier, 2015-06-06)
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development
of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid.
(Elsevier B.V., 2013-02-28)
Poly-(dl-lactic-co-glycolic) acid (PLGA) nanoparticles were prepared by a double emulsion solvent evaporation spray-drying technique and coated with polyethylene glycol (PEG 1% v/v). The PLGA nanoparticles had a small size ...
Spray-Dried, Nanoencapsulated, Multi-Drug Anti-Tuberculosis Therapy Aimed at OnceWeekly Administration for the Duration of Treatment
(MDPI, 2019-08-15)
Aiming to improve the treatment outcomes of current daily tuberculosis (TB) chemotherapy
over several months, we investigated whether nanoencapsulation of existing drugs would allow
decreasing the treatment frequency to ...