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Participatory Development of Practical, Affordable, Insecticide-Treated Mosquito Proofing for a Range of Housing Designs in Rural Southern Tanzania

Msoffe, Rogath; Hewitt, Matilda; Masalu, John; Finda, Marceline; Kavishe, Deogratius; Okumu, Fredros; Mpolya, Emmanuel; Kaindoa, Emmanuel; Killeen, Gerry (Research Square, 2022-02)

Background Insecticidal mosquito-proof netting screens could combine the best features of insecticide treated nets (ITNs) and indoor residual spraying (IRS), the two most important front line vector control interventions ...

Ribosomal/nucleolar stress induction regulates tert-Butyl hydroperoxide (tBHP) mediated oxidative stress in Anopheles gambiae midguts.

Tarimo, Brian; Hritzo, Bernadette; Law, Henry; Tao, Dingyin; Pastrana-Mena, Rebecca; Kanzok, Stefan; Buza, Joram; Dinglasan, Rhoel (BMC Research Notes, 2019-03-29)

Objective: A fundamental understanding of redox homeostasis in Anopheles gambiae midgut cells under different oxidative conditions is missing. Such knowledge can aid in the development of new malaria transmission-blocki ...

Genetic diversity of Plasmodium falciparum reticulocyte binding protein homologue-5, which is a potential malaria vaccine candidate: baseline data from areas of varying malaria endemicity in Mainland Tanzania

Kisambale, Angelina; Pereus, Dativa; Mandai, Salehe; Lyimo, Beatus; Bakari, Catherine; Chacha, Gervas; Mbwambo, Ruth; Moshi, Ramadhan; Petro, Daniel; Challe, Daniel; Seth, Misago; Madebe, Rashid; Budodo, Rule; Aaron, Sijenunu; Mbwambo, Daniel; Lusasi, Abdallah; Kajange, Stella; Lazaro, Samwel; Kapologwe, Ntuli; Mandara, Celine; Ishengoma, Deus (BioMed Central, 2025-01-27)

Background The limited efficacy of the two recently approved malaria vaccines, RTS,S/AS01 and R21/Matrix- M™, highlights the need for alternative vaccine candidate genes. Plasmodium falciparum Reticulocyte Binding Protein ...

Comparison of cone bioassay estimates at two laboratories with different Anopheles mosquitoes for quality assurance of pyrethroid insecticide-treated nets

Mbwambo, Stephen; Bubun, Nakei; Mbuba, Emmanuel; Moore, Jason; Mbina, Kasiani; Kamande, Dismas; Laman, Moses; Mpolya, Emmanuel; Odufuwa, Olukayode; Freeman, Tim; Karl, Stephan; Moore, Sarah (Springer Nature., 2022-07-07)

ckground: Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is con ducted by measuring physiochemical parameters, but not bioefcacy against malaria mosquitoes. This study ...

Effects of sample preservation methods and duration of storage on the performance of mid-infrared spectroscopy for predicting the age of malaria vectors

Mgaya, Jacqueline; Siria, Doreen; Makala, Faraja; Mgando, Joseph; Vianney, John Mary; Mwanga, Emmanuel; Okumu, Fredros (BMC, 2022-08-06)

Background Monitoring the biological attributes of mosquitoes is critical for understanding pathogen transmission and estimating the impacts of vector control interventions on the survival of vector species. Infrared ...

In starvation, a bone can also be meat”: a mixed methods evaluation of factors associated with discarding of long-lasting insecticidal nets in Bagamoyo, Tanzania

Madumla, Edith; Moore, Sarah; Moore, Jason; Mbuba, Emmanuel; Mbeyela, Edgar; Kibondo, Ummi; Mmbaga, Selemani; Kobe, Dickson; Baraka, Jitihada; Msellemu, Daniel; Swai, Johnson; Mboma, Zawadi; Odufuwa, Olukayode (Springer Nature., 2022-03-24)

Background: Between 2000 and 2019, more than 1.8 billion long-lasting insecticidal nets (LLINs) were distributed in Africa. While the insecticidal durability of LLINs is around 3 years, nets are commonly discarded 2 years ...

Long-lasting insecticidal nets retain bio-efficacy after 5 years of storage: implications for malaria control programmes

Musa, Jeremiah John; Moore, Sarah; Moore, Jason; Mbuba, Emmanuel; Mbeyela, Edgar; Kobe, Dickson; Swai, Johnson; Odufuwa, Olukayode (Springer Nature, 2020-03-14)

Background: Long-lasting insecticidal nets (LLINs) are the most sustainable and efective malaria control tool currently available. Global targets are for 80% of the population living in malaria endemic areas to have access ...

Antimalarial potential and phytochemical composition of fractions of Lippia kituiensis Vatke (Verbenaceae) growing in Northern Tanzania

Ng’etich, Japheth; Swai, Hulda; Njokah, Joseph; Wachira, Sabina; Koech, Lilian; Gathirwa, Jeremiah (Journal of Medicinal Plants Research, 2020-08-31)

Despite past decades of steady advances in the fight against Malaria, statistics show that the disease is still a threat to human health. Previous successes in the development of antimalarial drugs from medicinal plants ...

Cone Bioassays Provide Reproducible Bioefficacy Estimates with Different Anopheline Mosquitoes and Can Be Used for Quality Assurance of Pyrethroid Insecticide Treated Nets

Background Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is conducted by measuring physiochemical parameters, but not bioecacy against malaria mosquitoes. The cone ...

Risk of Aedes-borne diseases in and around the Tanzanian seaport of Tanga despite community members being more concerned about malaria

Abas, Amri; Simfukwe, Alfred; Masalu, John; Kahamba, Najat; Nambunga, Ismail; Msaky, Dickson; Limwagu, Alex; Kipekepeke, Abdallah; Wergin, Carsten; Njalambaha, Rukiyah; Kemibala, Elison; Seleman, Amour; Mlacha, Yeromin; Finda, Marceline; Beisel, Uli; Kimaro, Esther; Ngowo, Halfan; Okumu, Fredros (BioMed Central, 2024-12-18)

Background Increased global trade, while beneficial economically, can also increase the spread of vector-borne diseases, particularly those transmitted by Aedes mosquitoes spreading via trade routes. Given the heightened ...