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Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Inc., 2021-02-23)
The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug ...
Solvent effects on host-guest residence time and kinetics: further insights from metadynamics simulation of Toussaintine-A unbiding from chitosan nanoparticle
(Springer Nature, 2021-04-14)
Solvents play an important role in host-guest intermolecular interactions. The kinetics and residence time of Toussaintine-A (TouA) unbinding from chitosan was investigated by means of well-tempered metadynamics and ...
Performance characteristics and costs of serological tests for brucellosis in a pastoralist community of northern Tanzania
(Springer Nature Limited, 2021-03-09)
The control of brucellosis across sub-Saharan Africa is hampered by the lack of standardized testing and the use of tests with poor performance. This study evaluated the performance and costs of serological assays for human ...
Effects of agrochemicals on the beneficial plant rhizobacteria in agricultural systems
(Springer Nature, 2021-09-18)
Conventional agriculture relies heavily on chemical pesticides and fertilizers to control plant pests and diseases and improve production. Nevertheless, the intensive and prolonged use of agrochemicals may have undesirable ...
Advancement and practical applications of rhizobacterial biofertilizers for sustainable crop production in sub-Saharan Africa
(BioMed Central, 2021-12-13)
Agricultural intensification continues in Africa in attempts to meet the rising food demands of the equally rising
population. However, most arable lands in the region are characterized by nutrient deficiency and over-reliance ...
Activity of ethanolic extracts of spices grown in Tanzania against important fungal pathogens and early blight of tomato
(Bulgarian Journal of Agricultural Science, 2021-12)
The nutritional and economic value of tomato is universally recognized yet its production in many regions is still low due
to, among other reasons, fungal diseases. Farmers have desperately relied on synthetic chemical ...
Natural Pest Regulation and Its Compatibility with Other Crop Protection Practices in Smallholder Bean Farming Systems
(MDPI, 2021-08-20)
Common bean (Phaseolus vulgaris) production and storage are limited by numerous con-
straints. Insect pests are often the most destructive. However, resource-constrained smallholders in
sub-Saharan Africa (SSA) often do ...
Farmer-led feeding and breeding approaches for overcoming seasonality-driven milk fluctuations in smallholder dairy farms in Kenya and Tanzania
(NM-AIST, 2021-07)
Seasonality-driven changes in farmer-led feeding and breeding approaches are increasingly
captured as contributing to fluctuations in milk yield and reproductive performance of dairy
cows in smallholder dairy farms in ...
Iron and zinc genetic biofortification of yellow common bean (phaseolus vulgaris l.) genotypes in Tanzania
(NM-AIST, 2021-11)
Iron and zinc deficiencies are the global leading micronutrient deficiencies particularly in
developing countries such as Tanzania. Iron deficiency in humans causes anemia, whereas
zinc deficiency leads to compromised ...
Genome scan for signatures of adaptive evolution in wild African goat (capra nubiana)
(NM-AIST, 2021-08)
Nubian ibex (Capra nubiana) is a wild goat species inhabiting the Sahara and Arabia deserts. C.
nubiana thrives well in its habitat which is characterized by intense solar radiation, high
temperatures, little feed, and ...