Browsing Life sciences and Bio-engineering by Author "Shayo, Alex"
Now showing items 1-3 of 3
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Molecular marker of Plasmodium falciparum resistance to chloroquine (Pfcrt) in an area with long history of antimalarial resistance
Shayo, Alex; Ishengoma, Deus; Baraka, Vito; Madebe, Rashid; Shahada, Francis; Buza, Joram (American Journal of Research Communication, 2014)Background High levels Plasmodium falciparum resistance to Chloroquine (CQ) compelled Tanzania to replace CQ with Suphadoxine-pyrimethamine (SP) as first-line antimalarial in 2001 which was however replaced with Artemether ... -
Monitoring of efficacy and safety of artemisininbased anti-malarials for treatment of uncomplicated malaria: a review of evidence of implementation of anti-malarial therapeutic efficacy trials in Tanzania
Shayo, Alex; Buza, Joram; Ishengoma, Deus (BioMed Central, 2015)Background: Prompt diagnosis and effective treatment are considered the cornerstones of malaria control and artemisinin-based combination therapy (ACT) is currently the main anti-malarial drugs used for case management. After ... -
Therapeutic efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in North-Eastern Tanzania
Shayo, Alex; Mandara, Celine; Shahada, Francis; Buza, Joram; Lemnge, Martha; Ishengoma, Deus (BioMed Central, 2014)Background: The World Health Organization recommends that regular efficacy monitoring should be undertaken by all malaria endemic countries that have deployed artemisinin combination therapy (ACT). Although ACT is ...