Browsing Life sciences and Bio-engineering by Author "Naessens, Jan"
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CD5+ B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense-infected cattle
Buza, Joram; Sileghem, Maarten; Gwakisa, Paul; Naessens, Jan (Blackwell Science Ltd, 1997)Mice infected with African trypanosomes produce exceptionally large amounts of serum IgM, a major part of which binds to non-trypanosome antigens such as trinitrophenol and single-strand DNA. In this paper, we describe ... -
Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
Naessens, Jan; Mwangi, Duncan; Buza, Joram; Moloo, Shamshudeen (Blackwell Science Ltd, 2003)The first visible response in livestock to the bite of a trypanosomeinfected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated ... -
Trypanosome non-specific IgM antibodies detected in serum of Trypanosoma congolense-infected cattle are polyreactive
Buza, Joram; Naessens, Jan (Elsevier Science, 1999-07-01)Serum Ig from Trypanosoma congolense-infected cattle were affinity-purified using immobilised trypanosome or non-trypanosome antigens (ß-galactosidase, cytochrome C and ferritin). The bound and unbound IgG and IgM fractions ...