Browsing Life sciences and Bio-engineering by Author "Sauli, Elingarami"
Now showing items 21-35 of 35
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Mycobactericidal Effects of Different Regimens Measured by Molecular Bacterial Load Assay among People Treated for Multidrug-Resistant Tuberculosis in Tanzania
Mbelele, Peter; Mpolya, Emmanuel; Sauli, Elingarami; Mtafya, Bariki; Ntinginya, Nyanda; Addo, Kennedy; Kreppel, Katharina; Mfinanga, Sayoki; Phillips, Patrick; Gillespie, Stephen; Heysell, Scott; Sabiiti, Wilber; Mpagama, Stellah (American Society for Microbiology, 2021-02-03)Rifampin or multidrug-resistant tuberculosis (RR/MDR-TB) treatment has largely transitioned to regimens free of the injectable aminoglycoside component, despite the drug class’ purported bactericidal activity early in ... -
The neuroimaging magnitude of pediatric brain atrophy in northern Tanzania
Sungura, Richard Erasto; Spitsbergen, John Martin; Mpolya, Emmanuel; Sauli, Elingarami; Vianney, John-Mary (The Pan African Medical Journal, 2020-05-21)Introduction: the loss of parenchymal brain volume per normative age comparison is a distinctive feature of brain atrophy. While the condition is the most prevalent to elderly, it has also been observed in pediatric ages. ... -
Novel Multi-Linear Quantitative Brain Volume Formula For Manual Radiological Evaluation Of Brain Atrophy
Sungura, Richard Erasto; Mpolya, Emmanuel; Spitsbergen, J. M.; Onyambu, Callen Kwamboka; Sauli, Elingarami; John-Mary, Vianney (Research Square, 2020-06-22)The brain is a dynamic organ that develops and involutes in volume. The process of volume loss known as brain atrophy commonly occurs in elderly. However, some conditions have been implicated to provoke this paradoxical ... -
Performance of Tuberculosis Molecular Bacterial Load Assay Compared to Alere TB-LAM in Urine of Pulmonary Tuberculosis Patients with HIV Co-Infections
Mapamba, Daniel; Sauli, Elingarami; Lalashowi, Julieth; Buza, Joram; John, Joseph; Mwaisango, Zawadi; Tarmo, Peter; Sabi, Issa; Rachow, Andrea; Ntinginya, Nyanda; Mtafya, Bariki (MDPI, 2023-02-23)Alternative tools are needed to improve the detection of M. tuberculosis (M. tb) in HIV co-infections. We evaluated the utility of Tuberculosis Molecular Bacterial Load Assay (TB-MBLA) compared to lipoarabinomannan (LAM) ... -
Pesticide exposure and genotoxic effects as measured by DNA damage and human monitoring biomarkers.
Kapeleka, Jones; Sauli, Elingarami; Ndakidemi, Patrick (Taylor & Francis online, 2019-11-18)Occupational pesticides exposure rises health concern due to genotoxicity and accumulation of pesticides in human biological matrices. Continuous and sublethal exposure to pesticides had been associated with oxidative ... -
Plasmid characterization in bacterial isolates of public health relevance in a tertiary healthcare facility in Kilimanjaro region, Tanzania
Sengeruan, Lameck; Zwetselaar, Marco; Kumburu, Happiness; Aarestrup, Frank; Kreppel, Katharina; Sauli, Elingarami; Sonda, Tolbert (Elsevier, 2022-09)Objectives Plasmids are infectious double stranded DNA molecules that are found within bacteria. Horizontal gene transfer promotes successful spread of different types of plasmids within or among bacteria species, making ... -
Plasmid characterization in bacterial isolates of public health relevance in a tertiary healthcare facility in Kilimanjaro, Tanzania
Sengeruan, Lameck; van Zwetselaar, Marco; Kumburu, Happiness; Aarestrup, Frank; Kreppel, Katharina; Sauli, Elingarami (Elsevier, 2022-07-04)Objectives : Plasmids are infectious double stranded DNA molecules that are found within bacteria. Horizontal gene transfer promotes successful spread of different types of plasmids within or among bacteria species, making ... -
Porous Polyethylene Composite as Biomass Carrier for Red Pigment Production Using Monosodium Glutamate Wastewater as Medium
Li, Xiaolong; Zhang, Fengqin; Li, Taotao; Lu, Zhuoxuan; Zhang, Liming; Sauli, Elingarami; He, Nongyue (American Scientific Publishers, 2012-10-01)Abundant acidic wastewater from monosodium glutamate production is difficult to treat, leading to serious water pollution. Utilization of monosodium glutamate wastewater (MSGW) with high concentration of COD (33170 mg/L) ... -
Prevalence and associated risk factors for Kaposi’s sarcoma among HIV-positive patients in a referral hospital in Northern Tanzania: a retrospective hospital-based study
Semango, George; Charles, Renard; Swai, Consolata; Mremi, Alex; Amsi, Patrick; Sonda, Tolbert; Shao, Elichilia; Mavura, Daudi; Joosten, Leo; Sauli, Elingarami; Nyindo, Mramba (BMC, 2018-12-17)Background Kaposi’s sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS is an important AIDS-defining tumor with high prevalence in ... -
A review on methods for diagnosis of breast cancer cells and tissues.
He, Ziyu; Chen, Zhu; Tan, Miduo; Liu, Yuan; Li, Taotao; Deng, Yan; He, Nongyue; Li, Song; Fu, Juan; Li, Wen; Sauli, Elingarami (John Wiley & Sons Ltd, 2020-06-12)Breast cancer has seriously been threatening physical and mental health of women in the world, and its morbidity and mortality also show clearly upward trend in China over time. Through inquiry, we find that survival rate ... -
A Review on the Status of Breast Cancer Care in Tanzania
Mansouri, Hidaya; Mwakigonja, Amos R.; Rodgers, Faith A.; Mpolya, Emmanuel; Sauli, Elingarami (Multidisciplinary Cancer Investigation, 2020-07-01)Tanzania continues to enjoy stability and growth in different sectors similar to other countries; however, some challenges persist in the health sector, especially in the area of cancer care. The current study aimed at ... -
Seroprevalence of Hepatitis B Infection Among Blood Donors in the Western Zone of Tanzania
Marira, Gadiel; Kimaro, Esther; Sauli, Elingarami (preprint, 2024-04-30)Background In the western zone of Tanzania, there is limited information for the prevalence of hepatitis B infection. In this study, we analyzed the dataset of blood donors to determine seroprevalence and socio-demographic ... -
TB or not TB? Definitive determination of species within the Mycobacterium tuberculosis complex in unprocessed sputum from adults with presumed multidrug-resistant tuberculosis
Mbelele, Peter; Sauli, Elingarami; Mpolya, Emmanuel; Mohamed, Sagal; Addo, Kennedy; Mfinanga, Sayoki; Heysell, Scott; Mpagama, Stellah (John Wiley & Sons, Inc., 2021-06-09)objectives Differences among Mycobacterium tuberculosis complex (MTC) species may predict drug resistance or treatment success. Thus, we optimised and deployed the genotype MTBC assay (gMTBC) to identify MTC to the species ... -
TB or not TB? Definitive determination of species within the Mycobacterium tuberculosis complex in unprocessed sputum from adults with presumed multidrug-resistant tuberculosis
Mbelele, Peter; Sauli, Elingarami; Mpolya, Emmanuel; Mohamed, Sagal; Addo, Kennedy; Mfinanga, Sayoki; Heysell, Scott; Mpagama, Stellah (Tropical Medicine and International Health, 2021-06-09)Objectives Differences among Mycobacterium tuberculosis complex (MTC) species may predict drug resistance or treatment success. Thus, we optimised and deployed the genotype MTBC assay (gMTBC) to identify MTC to the species ... -
Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania
Mbelele, Peter; Utpatel, Christian; Sauli, Elingarami; Mpolya, Emmanuel; Mutayoba, Beatrice; Barilar, Ivan; Dreyer, Viola; Merker, Matthias; Sariko, Margaretha; Swema, Buliga; Mmbaga, Blandina; Gratz, Jean; Addo, Kennedy; Pletschette, Michel; Niemann, Stefan; Houpt, Eric; Mpagama, Stellah; Heysell, Scott (Oxford University Press, 2022-04-21)Background: Rifampicin- or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis complex (MTBC) strains account for considerable morbidity and mortality globally. WGS-based prediction of drug resistance may guide clinical ...