Browsing Life sciences and Bio-engineering by Author "Shirima, Gabriel"
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African Swine Fever Virus (ASFV): Biology, Genomics and Genotypes Circulating in Sub-Saharan Africa
Njau, Emma; Machuka, Eunice; Cleaveland, Sarah; Shirima, Gabriel; Kusiluka, Lughano; Okoth, Edward; Pelle, Roger (MDPI, 2021-11-15)African swine fever (ASF) is a highly infectious and fatal haemorrhagic disease of pigs that is caused by a complex DNA virus of the genus Asfivirus and Asfarviridae African suids family. The disease is among the most ... -
Antimicrobial resistant coliforms across four poultry production systems in Arusha and Moshi, Tanzania
Maganga, Ruth; Sindiyo, Emmanuel; Musyoki, Victor; Shirima, Gabriel; Maina, Brian; Mmbaga, Blandina (Pan African Medical Journal, 2022-01-11)Introduction: resistance to antimicrobials poses a threat to human and animal health. This study aimed to determine the prevalence of resistant coliforms in poultry cloacal samples collected from different poultry ... -
Assessment of Knowledge, Attitude and Practices (KAP) on Hantavirus Infections at Community Level in Mbeya Region, Tanzania
Sudi, Lwitiho; Mangu, Chacha; Ntinginya, Elias; Shirima, Gabriel; Tarimo, Mokiti (Longdom Publishing., 2018-10-26)Background: Hantaviruses are zoonotic RNA viral pathogens of public health concern in Tanzania and worldwide. These viruses circulate in both human and reservoir host in Tanzania, however, there is a gap in the assessment ... -
A case-control study on the driving factors of childhood brain volume loss: What pediatricians must explore
Sungura, Richard; Shirima, Gabriel; Spitsbergen, John; Mpolya, Emmanuel; Vianney, John-Mary (PLOS ONE, 2022-12-30)Background The brain volume loss also known as brain atrophy is increasingly observed among children in the course of performing neuroimaging using CT scan and MRI brains. While severe forms of brain volume loss are ... -
Combining Multiple Assays Improves Detection and Serotyping of Foot-and-Mouth Disease Virus. A Practical Example with Field Samples from East Africa
Foglia, Efrem; Lembo, Tiziana; Kazwala, Rudovick; Ekwem, Divine; Shirima, Gabriel; Grazioli, Santina; Brocchi, Emiliana; Pezzoni, Giulia (MDPI, 2021-08-10)Multiple serotypes and topotypes of foot-and-mouth disease virus (FMDV) circulate in endemic areas, posing considerable impacts locally. In addition, introductions into new areas are of great concern. Indeed, in recent ... -
Comparative analysis of clinical breakpoints, normalized resistance interpretation and epidemiological cut-offs in interpreting antimicrobial resistance of Escherichia coli isolates originating from poultry in different farm types in Tanzania
Maganga, Ruth; Sindiyo, Emmanuel; Musyoki, Victor; Shirima, Gabriel; Mmbaga, Blandina (Microbiology Society, 2014-07-14)Introduction. Existing breakpoint guidelines are not optimal for interpreting antimicrobial resistance (AMR) data from animal studies and low-income countries, and therefore their utility for analysing such data is limited. ... -
Complete genome sequence of Brucella abortus isolated from a human blood culture sample in Tanzania
Mbwambo, Gershom; Zwetselaar, Marco; Sonda, Tolbert; Lukambagire, AbdulHamid; Njau, Judith; Wadugu, Boaz; Ignass, Ignass; Amani, Nelson; Hugho, Ephrasia; Rubach, Matthew; Sakasaka, Philoteus; Oisso, Rose; Mkenda, Nestory; Shirima, Gabriel; Ashford, Roland; Haydon, Daniel; Maro, Venance; Kazwala, Rudovick; Kumburu, Happiness; Mmbaga, Blandina; Halliday, Jo E. (American society for microbiology, 2024-01-30)Brucella abortus causes infections in humans and livestock. Bacterial isolates are challenging to obtain, and very little is known about the genomic epidemiology of this species in Africa. Here, we report the complete ... -
Conjugative Plasmids Disseminating CTX-M-15 among Human, Animals and the Environment in Mwanza Tanzania: A Need to Intensify One Health Approach
Minja, Caroline; Shirima, Gabriel; Mshana, Stephen (MDPI, 2021-07-09)Background: Globally, blaCTX-M-15 beta-lactamases are the most popular extended spectrum beta-lactamase alleles that are widely distributed due its mobilisation by mobile genetic elements in several compartments. We aimed ... -
Current State of Modern Biotechnological-Based Vaccines for Aquaculture: A Systematic Review.
Mzula, Alexanda; Wambura, Philemon; Mdegela, Robinson; Shirima, Gabriel (Hindawi, 2019-07-29)This systematic review describes what "the cutting edge vaccines for are". The focus is on types of high tech biotechnological based vaccines, target gene or antigen in developing these vaccines, and challenge model fish ... -
Detection of African swine fever virus genotype XV in a sylvatic cycle in Saadani National Park, Tanzania
Njau, Emma; Machuka, Eunice; Githae, Dedan; Okoth, Edward; Cleaveland, Sarah; Shirima, Gabriel; Kusiluka, Lughano; Pelle, Roger (Wiley Online Library, 2020-07-22)African swine fever (ASF) is a severe haemorrhagic disease of domestic pigs caused by ASF virus (ASFV). ASFV is transmitted by soft ticks (Ornithodoros moubata complex group) and by direct transmission. In Africa, ASF ... -
Detection of carrier state and genetic diversity of Theileria parva in ECF-vaccinated and naturally exposed cattle in Tanzania
Magulu, Emelesiana Cyprian; Kindoro, Fatuma; Mwega, Elisa; Kimera, Sharadhuli; Shirima, Gabriel; Gwakisa, Paul (Elsevier B.V., 2019-08)Infection and Treatment Method (ITM) has been practiced in Tanzania for over 20 years as a prevention measure against East Coast Fever disease. It is known that ITM, like natural ECF infection, leads to a carrier state, ... -
Detection of Contagious Caprine Pleuropneumonia and Concurrent Diseases in Outbreaks Presenting with Respiratory Signs in Small Ruminants in Tanzania
Chota, Andrew; Shirima, Gabriel; Kusiluka, Lughano (International Journal of TROPICAL DISEASE & Health, 2020-07-06)Aims: To establish the prevalence and concurrent diseases in outbreaks presenting with respiratory signs, major associated clinical signs and postmortem lesions and proportions of those diseases in clinically and autopsied ... -
Detection of peste des petits ruminants and concurrent secondary diseases in sheep and goats in Ngorongoro district, Tanzania
Kgotlele, Tebogo; Chota, Andrew; Chubwa, Choby; Nyasebwa, Obed; Lyimo, Beatus; Torsson, Emeli; Karimuribo, Esron; Kasanga, Christopher; Wensman, Jonas; Misinzo, Gerald; Shirima, Gabriel; Kusiluka, Lughano (Springer, 2018-11-15)Small ruminants play an important role in the livelihoods of resource-constrained communities. This study was initiated because of a massive outbreak of a respiratory disease in sheep and goats in Loliondo area in Ngorongoro ... -
Determinants of Dogs’ Helminth Treatment-Seeking Behavior among Dog Owners in Rural Northern Tanzania.
Kibona, Tito; Buza, Joram; Shirima, Gabriel (Pre prints.org, 2024-02-20)Taeniid infections pose a significant threat to both animal and public health, as certain tapeworms within this group can also infect humans, potentially leading to severe health conditions. Therefore, this calls for ... -
Determinants of Dogs’ Helminth Treatment-Seeking Behavior among Dog Owners in Rural Northern Tanzania: Towards Control of Taenia multiceps, an Emerging Threat to Small Ruminants’ Productivity
Kibona, Tito; Buza, Joram; Shirima, Gabriel (Preprints, 2024-02-20)Taeniid infections pose a significant threat to both animal and public health, as certain tapeworms within this group can also infect humans, potentially leading to severe health conditions. Therefore, this calls for ... -
Diagnosis Challenges and Control Strategies of Transboundary Diseases Presenting with Respiratory Signs in Small Ruminants in Developing Countries: Emphasis on Contagious Caprine Pleuropneumonia and Peste Des Petits Ruminants
Chota, Andrew; Shirima, Gabriel; Kusiluka, Lughano (International Journal of TROPICAL DISEASE & Health, 2020-12-31)Aims: To review the diagnosis challenges and control strategies of the diseases presenting with respiratory signs. The emphasis being more on two transboundary animal diseases of small ruminants; contagious caprine ... -
Diagnostic challenges of brucellosis in humans and livestock in Tanzania: A thematic review
Mengele, Isaac; Shirima, Gabriel; Bronsvoort, Barend; Hernandez-Castro, Luis; Cook, Elizabeth (CABI One Health, 2023-01-13)Brucellosis is an endemic bacterial zoonosis in Tanzania, and is among the most prioritized zoonotic diseases in the country. Brucellosis affects public health and livestock production in developing countries. Most human ... -
Drivers of vaccination preferences to protect a low-value livestock resource: Willingness to pay for Newcastle disease vaccines by smallholder households.
Campbell, Zoë; Otieno, Linus; Marsh, Thomas; Palmer, Guy; Shirima, Gabriel (Elsevier Ltd., 2019-01-03)Vaccination can be an effective risk management approach to minimize the burden of disease and increase livestock productivity for smallholder households in low income countries. In contrast to vaccination of cattle, a ... -
Enhancing livestock vaccination decision-making through rapid diagnostic testing
Railey, Ashley; Lankester, Felix; Lembo, Tiziana; Reeve, Richard; Shirima, Gabriel; Marsh, Thomas (Elsevier Ltd., 2019-12)• Compared to vaccination, the collective approach to diagnostic testing presents a low-fixed cost. • Existing household livestock-health behaviors increase the likelihood for uptake of preventative health practices. ... -
Entomopathogenic fungi (Aspergillus oryzae) as biological control agent of cattle ticks in Tanzania
Msangi, Sylvia; Zekeya, Never; Kimaro, Esther; Kusiluka, Lughano; Shirima, Gabriel (Academic Journals, 2022-07-31)Ticks are the most important ectoparasites that are responsible for severe economic losses in livestock industry. The use of chemical acaricides is the most common method used to control ticks in livestock. This study ...