In vitro Antimycobacterial Activity of Sterculia quinqueloba (Garcke) K. Schumand Canthium crassum Hiern

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dc.contributor.author Wilson, Elihuruma
dc.contributor.author Chacha, Musa
dc.contributor.author Omolo, Justin
dc.date.accessioned 2021-02-18T11:27:45Z
dc.date.available 2021-02-18T11:27:45Z
dc.date.issued 2015-01-06
dc.identifier.uri https://doi.org/10.9734/EJMP/2015/14950
dc.identifier.uri https://dspace.nm-aist.ac.tz/handle/20.500.12479/1125
dc.description This research article published European Journal of Medicinal Plants, 2015 en_US
dc.description.abstract Aim: To screen for the anti-mycobacterial activity of Canthium crassum and Sterculia quinqueloba using two mycobacteria species the Mycobacteria madagascariense and Mycobacteria indicuspranii. Study Design: In vitro assay of anti-mycobacterial assay was done using 96-well micro-dilution method. Place and Duration of Study: School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania, from April 2014 to June 2014. Methodology: 96-well-microtitre serial micro-dilution method was used to determine anti-mycobacteria activity to plant extracts. Results: All extracts exhibited anti-mycobacterial activity to both mycobacteria tested. The minimum inhibition concentration (MIC) ranged from 0.39 – 12.5 mg/mL, with ethyl acetate leaf extract of S. quinqueloba being the most active extracts with MIC value of 0.39 mg/mL against Mycobacteria madagascariense (MM) and 0.78 mg/mL against Mycobacteria indicuspranii (MIP). Petroleum ether and ethyl acetate leaf extract of C. crassum also gave MIC value of 0.78 mg/mL against MM and MIP. Conclusion: Findings from the present study showed that both plants exhibited activity against mycobacterium species tested. These plants may therefore serve as a source for new ant-mycobacterium drugs worth further studies including isolation and identification of the active compounds. en_US
dc.language.iso en en_US
dc.publisher European Journal of Medicinal Plants en_US
dc.subject Anti-mycobacterial en_US
dc.subject Canthium crassum en_US
dc.subject Sterculia quinqueloba en_US
dc.title In vitro Antimycobacterial Activity of Sterculia quinqueloba (Garcke) K. Schumand Canthium crassum Hiern en_US
dc.type Article en_US

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