Prevalence and predictors of self-medication with antibiotics in selected urban and rural districts of the Dodoma region, Central Tanzania: a cross-sectional study
| dc.contributor.author | Mabilika, Richard | |
| dc.contributor.author | Mpolya, Emmanuel | |
| dc.contributor.author | Shirima, Gabriel | |
| dc.date.accessioned | 2022-08-24T12:58:34Z | |
| dc.date.available | 2022-08-24T12:58:34Z | |
| dc.date.issued | 2022-06-22 | |
| dc.description | This research article was published by Springer Nature, 2022 | en_US |
| dc.description.abstract | Background: Antibiotic resistance is a global health threat driven partly by self-medication with antibiotics (SMA). This study aims to assess the prevalence and predictors of SMA in selected rural and urban communities of the Dodoma region, Central Tanzania. Methods: This cross-sectional study was conducted in Chemba District Council (rural) and Dodoma City Council (urban) from August to November 2019 using multistage stratifed random sampling. Data were collected through face-to-face interviews using structured questionnaires. Results: A total of 430 respondents were interviewed in Chemba District Council (rural) (161/430) and Dodoma City Council (urban) (269/430). The prevalence of SMA was 23.6% (38/161) among rural respondents and 23.4% (63/269) among urban respondents. The median amount of SMA in both settings was 2, while the maximum amounts were 4 and 5, respectively. SMA among rural and urban participants was associated mostly with perceived cough (76.3%/82%), body pain (71.1%/41.5%) and fever (63.2%/39.7%), and amoxicillin was the most commonly used antibiotic in both settings (47.3%/41%). Rural participants who reported a shorter perceived distance to a health care facility than to a drug outlet were 58.9% less likely to practise SMA (adjusted OR: 0.421; 95% CI: 0.388, 0.458; p<0.001), whereas SMA decreased by 16.3% among urban participants who reported a shorter perceived distance to a health care facility than to a drug outlet (adjusted OR: 0.837; 95% CI: 0.755, 0.929; p<0.001). SMA was 17.3% lower among farmers than among nonfarmers in the urban area (adjusted OR: 0.827; 95% CI: 0.716, 0.955; p=0.01), while farming had no efect in the rural area. Conclusions: The prevalence of SMA is similar among participants in rural and urban districts. In both localities, a shorter perceived distance to a drug outlet is an independent risk factor for SMA, while having health insurance reduces the risk. Equally weighted interventions to reduce SMA are required in rural and urban communities. | en_US |
| dc.identifier.uri | https://doi.org/10.1186/s13756-022-01124-9 | |
| dc.identifier.uri | https://dspace.nm-aist.ac.tz/handle/20.500.12479/1491 | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer Nature. | en_US |
| dc.subject | Antibiotics | en_US |
| dc.subject | Self-medication | en_US |
| dc.subject | Sociodemographics | en_US |
| dc.subject | Drug outlet | en_US |
| dc.title | Prevalence and predictors of self-medication with antibiotics in selected urban and rural districts of the Dodoma region, Central Tanzania: a cross-sectional study | en_US |
| dc.type | Article | en_US |