Creating mosquito-free outdoor spaces using transfluthrin-treated chairs and ribbons

dc.contributor.authorPaliga, John
dc.date.accessioned2020-11-18T08:52:45Z
dc.date.available2020-11-18T08:52:45Z
dc.date.issued2020-03
dc.descriptionA Dissertation Submitted in Partial Fulfillment of the Requirement for the Degree of Master of Science in Public Health Research of the Nelson Mandela African Institution of Science and Technologyen_US
dc.description.abstractResidents of malaria-endemic communities spend several hours outdoors performing different activities such as cooking, story-telling or eating; thereby exposing themselves to potentially-infectious mosquitoes. This compromises indoor interventions, notably longlasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS). This study characterized common peri-domestic spaces in rural south-eastern Tanzania, and assessed protective efficacies of transluthrin-treated chairs and hessian ribbons against mosquitoes. Two hundred households were surveyed, and their most-used peri-domestic spaces physically characterized. Protective efficacies of these two prototyped interventions were tested outdoor in 28 households in dry and wet seasons, using volunteer-occupied exposure-free double net traps. Center for Diseases Control and Prevention miniature light traps (CDC-LT) were used to estimate host-seeking mosquito densities within outdoor kitchens. Field-collected Anopheles arabiensis and Anopheles funestus mosquitoes were exposed underneath the chairs to estimate 24h-mortality. Approximately half (52%) of houses had verandas. Aside from these verandas, most houses also had peri-domestic spaces where residents stayed most times (67% of houses with verandas and 94% of non-veranda houses). Transfluthrin-treated chairs reduced outdoor-biting An. arabiensis densities by 70-85 % while transfluthrin-treated hessian ribbons caused 77-81% reduction in the general peri-domestic area. Field-collected An. arabiensis (99.4%) and An. funestus (100%) exposed under transfluthrin-treated chairs died. Most houses had actively-used peri-domestic spaces where exposure to mosquitoes occurred. The transfluthrin-treated chairs and ribbons reduced outdoor-biting malaria vectors in these peri-domestic spaces, and also elicited significant mortality among pyrethroid-resistant fieldcaught malaria vectors. These two new prototypes, if developed further, may constitute new options for complementing LLINs and IRS with outdoor protection against malaria and other mosquito-borne pathogens in areas where peri-domestic human activities are common.en_US
dc.identifier.urihttps://doi.org/10.58694/20.500.12479/1007
dc.language.isoenen_US
dc.publisherNM-AISTen_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectPeri-domestic spacesen_US
dc.subjectTransfluthrin-treated chairsen_US
dc.subjectHessian ribbonsen_US
dc.subjectSpatial repellentsen_US
dc.subjectOutdoor-bitingen_US
dc.subjectMalaria vectorsen_US
dc.titleCreating mosquito-free outdoor spaces using transfluthrin-treated chairs and ribbonsen_US
dc.typeThesisen_US

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