Browsing Research Articles [MEWES] by Author "Rubaka, Clarence"
Now showing items 1-3 of 3
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Chitosan-coated liposomes of Carrisa spinarum extract: synthesis, analysis and anti-pneumococcal potency
Rubaka, Clarence; Gathirwa, Jeremiah; Malebo, Hamisi; Swai, Hulda; Sibuyi, Nicole; Hilonga, Askwar; Dube, Admire (ICE Publishing, 2023-02-16)In the present study, a chitosan (CS)-coated liposome (LipCsP-Chitosan) nanocarrier was fabricated for the delivery of Carissa spinarum (CsP) polyphenols to improve bioavailability and anti-pneumococcal potential against ... -
Development and Characterization of Nanovesicles Containing Phenolic Compounds of Carissa spinarum: Encapsulation, Release Kinetics, Antimicrobial Activity and Mathematical Modeling
Rubaka, Clarence; Gathirwa, Jeremiah; Malebo, Hamisi; Swai, Hulda; Hilonga, Askwar (Trans Tech Publications Ltd, 2023-05)The aim of this study was to develop and characterize a delivery system for polyphenols from an extract of Carissa spinarum leaves, based on liposomes. Liposomes loaded with Carissa spinarum polyphenols (nanoliposomal CsP) ... -
Inorganic Nanocarriers: Surface Functionalization, Delivery Utility for Natural Therapeutics - A Review
Rubaka, Clarence; Gathirwa, Jeremiah; Malebo, Hamisi; Swai, Hulda; Hilonga, Askwar (Scientific.Net, 2022-08)Inorganic nanocarriers for a decade have increased interest in nanotechnology research platform as versatile drug delivery materials. The utility of the inorganic nanocarriers for delivery of therapeutic agents is attributed ...