Browsing Computational and Communication Science Engineering by Author "Kashaju, Nelson"
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Modeling the Effect of Binding Kinetics in Spatial Drug Distribution in the Brain
Kashaju, Nelson; Kimathi, Mark; Masanja, Verdiana Grace (Hindawi, 2021-07-05)A 3-dimensional mathematical model is developed to determine the effect of drug binding kinetics on the spatial distribution of a drug within the brain. The key components, namely, transport across the blood-brain barrier ... -
Modeling the effect of binding kinetics in spatial drug distribution in the brain
Kashaju, Nelson (NM-AIST, 2021-08)Key factors in the process of drug delivery in the human brain are blood-brain barrier, drug dis tribution and drug binding kinetics. Since human brain is entirely unavailable for experimenta tion, mathematical models have ...