Browsing by Author "Sauli, E"

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    Biological properties of extracts from locally grown banana leaves indicate their possible use for wound dressing in Arusha, Tanzania
    (Embase, 2021-10-01) Telesphory, A; Grosche, S; Vianney, J.M; Sauli, E; Swai, H
    This study assessed the biological properties and safety profile of extracts from locally grown banana leaves in Arusha (Tanzania), to affirm their possible use for wound dressing. Screening for phytoconstituents in extracts from studied banana plant species, ijuhi inkundu (IJ) mlelembo (ML) and kimalindi (KIM), revealed the presence of various secondary metabolites; anthraquinones, alkaloids, flavonoids, tannins, terpenoids, phenols, phytosterol and saponins. Susceptibility of microorganisms to studied banana varieties were in the order of KIM > ML > IJ. One-way analysis of variance (ANOVA) revealed a statistical difference of mean among all extracts (p < 0.05). Antioxidant activity was evaluated by measuring the ability of extracts to scavenge DPPH free radicals. Scavenging of DPPH was in the order of > kimalindi > ijuhi inkundu > mlelembo. Brine shrimp results for toxicity showed that almost all extracts were non-toxic to the shrimps, exhibiting mild toxicity by giving the LC50 values higher than 100 µg/mL.
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    The extended scope of neuroimaging and prospects in brain atrophy mitigation: A systematic review
    (Elsevier, 2021-03) Sungura, R; Onyambu, C; Mpolya, E; Sauli, E; Vianney, J-M
    Brain atrophy is a condition associated with a reduction of brain volume. It is a common manifestation of aging even though it occurs in some childhood conditions and carried forward to pre-senile middle age. There are several causes of brain atrophy resulting in different patterns of brain volume loss which spans from focal, global, central, cortical, and hemiatrophy. These conditions are commonly associated with other neurodegenerative changes that lead to different dysfunctions. Neuroimaging is critical for the diagnosis, evaluation of lesions and quantification of the atrophy. However, radiological quantification of brain volume is done by both automated and manual methods to study brains basing a wide variation of cranial sizes and shapes. A multidisciplinary approach is the future of brain atrophy management. An extended scope of knowledge beyond image interpretation is inevitable.