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Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis
(Elsevier, 2015-06-06)
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development
of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
Nanoencapsulation of water-soluble drug, lamivudine, using a double emulsion spray-drying technique for improving HIV treatment
(Springer Nature Switzerland AG., 2013-10-22)
Current treatments available for human immunodeficiency virus, namely antiretrovirals, do not
completely eradicate the virus from the body, leading to life-time commitment. Many
antiretrovirals suffer drawbacks from ...
Luteolin: a blocker of SARS-CoV-2 cell entry based on relaxed complex scheme, molecular dynamics simulation, and metadynamics
(Springer Nature, 2021-07-08)
Natural products have served human life as medications for centuries. During the outbreak of COVID-19, a number of
naturally derived compounds and extracts have been tested or used as potential remedies against COVID-19. ...
In vitro antiproliferative potential of crude extracts from Carica papaya L. (Caricaceae) black seeds against prostate cancer cell lines'
(American Journals, 2022-04-30)
Black seeds from papaya plants are utilized as traditional medicine in African and Asian cultures to
improve the functioning of the male reproductive system and management of prostate cancer. This
study analyzed the ...
Formulation, Optimization, and Evaluation of Moringa oleifera Leaf Polyphenol-Loaded Phytosome Delivery System against Breast Cancer Cell Lines
(MDPI, 2022-07-11)
Moringa oleifera leaf polyphenols (Mopp) were encapsulated with phytosomes to enhance their efficacy on 4T1 cancer cell lines. The Mopp were extracted via microwave-assisted extraction. Moringa oleifera polyphenol-loaded ...
Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
(Dove Press, 2019-04-26)
Aim: This study aimed to evaluate larvicidal activity of Hypoestes forskaolii R. Br root
extract against 3rd instar Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus.
Methods: A protocol developed by the World ...
Mobile application development framework to support farming as a business via benchmarking: the case of Tanzania
(International Journal of Advanced Computer Research (IJACR), 2019-11)
Contributions from various researchers and scholars have made major advances relevant to a wide range of mobile
applications at various scales. Although current agricultural and rural development (ARD) systems have features ...
Microalgae: An alternative natural source of bioavailable omega-3 DHA for promotion of mental health in East Africa
(Elsevier, 2019-10-11)
Mental health illness associated with poor nutrition is a serious public concern worldwide. The most at risk individuals are children and adolescents in the developing world. Deficiencies in omega-3 DHA fatty acids have ...
Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles.
(Elsevier, 2016-04-01)
Effective use of dihydroartemisinin (DHA) is limited by poor water-solubility, poor pharmacokinetic profile and unsatisfactory clinical outcome especially in monotherapy. To reduce such limitations, we reformulated DHA ...
State of the art and future directions in nanomedicine for tuberculosis.
(Expert Opinion on Drug Delivery, 2013-12-01)
Introduction: Tuberculosis (TB) ranks the second leading cause of death from an infectious disease worldwide. However, treatment of TB is affected by poor patient compliance due to the requirement for daily drug administration, ...