Browsing Life sciences and Bio-engineering by Title
Now showing items 354-373 of 1024
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Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Ltd., 2021-06)The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational ... -
Ensemble-based screening of natural products and FDA-approved drugs identified potent inhibitors of SARS-CoV-2 that work with two distinct mechanisms
(Elsevier Inc., 2021-02-23)The recent outbreak of SARS-CoV-2 is responsible for high morbidity and mortality rate across the globe. This requires an urgent identification of drugs and other interventions to overcome this pandemic. Computational drug ... -
Entomopathogenic fungi (Aspergillus oryzae) as biological control agent of cattle ticks in Tanzania
(Academic Journals, 2022-07-31)Ticks are the most important ectoparasites that are responsible for severe economic losses in livestock industry. The use of chemical acaricides is the most common method used to control ticks in livestock. This study ... -
Environmental and genotypes influence on seed iron and zinc levels of landraces and improved varieties of common bean (Phaseolus vulgaris L.) in Tanzania
(Elsevier, 2020-05)Phaseolus vulgaris L. (common bean) is a grain legume rich in proteins and micronutrients particularly iron and zinc. This study determined the concentration of iron and zinc in 99 common bean genotypes (landraces and ... -
Environmental factors and non-chemical methods to suppress growth of the invasive plant Gutenbergia cordifolia
(Elsevier, 2023-08-01)Little is known about preferred environmental conditions and non-chemical control of invasive Gutenbergia cordifolia. We assessed the effects of different A. annua crude extract concentrations, synthetic herbicide (glyphosate), ... -
Environmental risks of a commonly used pyrethroid: Insights from temporary pond species of the Lake Manyara Basin, Tanzania
(Elsevier, 2023-01)Environmental risks posed by widespread pesticide application have attracted global attention. Currently, chemical risk assessments in aquatic environments rely on extrapolation of toxicity data from classic model species. ... -
Environmentally stable common bean genotypes for production in different agro-ecological zones of Tanzania
(Heliyon, 2021-01-19)enotype by environment interaction (GxE) complicates the process of selecting genotypes suitable for quanti tative traits like seed yield in beans, hence slows down the development and release of varieties by breeding programs. ... -
Epidemiology and Economic Importance of African Animal Trypanosomiasis
(IGI Global, 2021)African animal trypanosomiasis (AAT), also called Nagana, is a vector-borne parasitic disease caused by an extracellular protozoan belonging to the genus Trypanosoma. It has serious effects on the health status and welfare ... -
Epidemiology and impact of foot-and-mouth disease in districts located along the Uganda and Tanzania border
(2020-03)The Uganda-Tanzania border area lies within the main risk areas for foot-and-mouth disease (FMD) circulation. With the introduction of the progressive control pathway for FMD in eastern Africa, reliable information on ... -
Epidemiology of intestinal schistosomiasis and efficacy of single versus repeated dose praziquantel treatments among schoolchildren in Rorya district, Northwestern Tanzania
(NM-AIST, 2018-12)In Schistosoma mansoni endemic areas, administering repeated treatments may increase praziquantel cure rate (CR) and egg reduction rate (ERR), thereby improving morbidity reduction and hastening achievement of transmission ... -
Epidemiology of intestinal schistosomiasis and efficacy of single versus repeated dose praziquantel treatments among schoolchildren in Rorya district, Northwestern Tanzania
(NM-AIST, 2018-12)In Schistosoma mansoni endemic areas, administering repeated treatments may increase praziquantel cure rate (CR) and egg reduction rate (ERR), thereby improving morbidity reduction and hastening achievement of transmission ... -
Epidemiology of leptospirosis in Tanzania: A review of the current status, serogroup diversity and reservoirs
(PLOS, 2021-11-16)Background Tanzania is among the tropical countries of Sub-Saharan Africa with the environmental conditions favorable for transmission of Leptospira. Leptospirosis is a neglected zoonotic disease, and although there are ... -
Epidemiology of Newcastle disease in poultry in Africa: systematic review and meta-analysis
(Springer Nature, 2022-06-15)The present study intended to determine the prevalence of Newcastle disease in unvaccinated backyard poultry in Africa. Using the PRISMA approach, a systematic review and meta-analysis of 107 epidemiological studies was ... -
Epidemiology of Q-fever in domestic ruminants and humans in Africa. A systematic review
(CABI One Health, 2022-11-17)Q-fever is a zoonotic infectious disease caused by the gram-negative, intracellular, spore-forming bacterium Coxiella burnetii . Infected ruminants (cattle, sheep, and goats) are the reservoirs of the pathogen and thus ... -
Epidemiology, risk factors and diagnostic accuracy of surveillance methods of selected diseases presenting with respiratory signs in small ruminants in Tanzania
(NM-AIST, 2021-07)Outbreaks of diseases presenting with respiratory signs in small ruminants in Tanzania have been reported for years. Concurrent infections complicate diagnosis resulting in untimely interventions and significant economic ... -
Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data.
(PLOS ONE, 2021-03-11)Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support aflatoxin mitigation measures. In this study, we estimated aflatoxin-induced ... -
Ethical considerations in the design and conduct of a cluster-randomised mycotoxin mitigation trial in Tanzania
(Wageningen Academic Publishers, 2022-01-24)Aflatoxins are fungal metabolites that commonly contaminate staple food crops in tropical regions. Acute aflatoxin consumption in very high concentration causes aflatoxicosis and acute liver failure, while chronic, moderate ... -
Ethical Considerations of the Trial to Establish a Causal Linkage Between Mycotoxin Exposure and Child Stunting
(Elsevier, 2021-06-21)Objectives Aflatoxins are fungal metabolites that commonly contaminate staple crops in tropical regions. Aflatoxin is a carcinogen and consumption at high-levels can lead to acute liver failure and aflatoxicosis. Multiple ... -
Ethnobiological survey to determine the link between health benefits and qualities of Maasai traditional food system in Monduli, Arusha, Tanzania
(Taylor & Francis, 2023-07)Although Maasai’s traditional food system (TFS) is claimed to keep a low prevalence of metabolic diseases (MD), the link between its qualities and health benefits is not well established. An ethnobotanical survey was ... -
Ethnobotanical Survey of Flora Used in Maasai Food System and Traditional Medicine against Gout-related and Other Human Ailments in Monduli, Arusha, Tanzania
(Research Square, 2021-09-01)Background: Flora used by Maasai practitioners (MSPs) in traditional medicine (TM) and food system (FS) were investigated in Monduli District, Arusha, Tanzania. The objective of this study was to document the knowledge on ...