Browsing Life sciences and Bio-engineering by Title
Now showing items 177-196 of 1021
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Comparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes
(Taylor & Francis Group., 2019-04-22)Nanoparticles (NPs) have gained importance in addressing drug delivery challenges across biological barriers. Here, we reformulated pentamidine, a drug used to treat Human African Trypanosomiasis (HAT) in polymer based ... -
Comparison of antibiotic resistant Escherichia coli obtained from drinking water sources in northern Tanzania: a cross-sectional study
(BMC Microbiology, 2016)Background: Antimicrobial resistance (AMR) is a growing and significant threat to public health on a global scale. Escherichia coli comprises Gram-negative, fecal-borne pathogenic and commensal bacteria that are ... -
Comparison of cone bioassay estimates at two laboratories with different Anopheles mosquitoes for quality assurance of pyrethroid insecticide-treated nets
(Springer Nature., 2022-07-07)ckground: Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is con ducted by measuring physiochemical parameters, but not bioefcacy against malaria mosquitoes. This study ... -
Comparison of cone bioassay estimates at two laboratories with different anopheles mosquitoes for quality assurance of pyrethroid insecticide-treated nets
(NM-AIST, 2022-08)This study explored utility of cone bioassays for pre-delivery quality assurance (QA) of pyrethroid insecticide-treated nets (ITNs) to test the assumption that cone bioassays are consistent across locations, mosquito ... -
Comparison of the effects of a broad-spectrum herbicide and a bio-herbicide on insect flower visitation in the Serengeti ecosystem, Tanzania
(Elsevier, 2021-12)The functional role of insect visitors on flowering plants is crucial to both natural and agricultural ecosystems. While, few studies have addressed the impact of invasive plant species on insect visitors, even less is ... -
Comparison of the prevalence of antibiotic-resistant Escherichia coli isolates from commercial-layer and free-range chickens in Arusha district, Tanzania
(African Journal of Microbiology Research, 2016-09-14)The antibiotic susceptibility of fecal Escherichia coli isolates from commercial-layer and free-range chickens in Arusha district, Tanzania were compared. All the chickens were raised by individual households, but ... -
Complementary feeding in Kongwa, Tanzania: Findings to inform a mycotoxin mitigation trial.
(John Wiley & Sons Ltd., 2021-05-04)Complementary feeding of 6- to 24-month-old infants and young children with adequate, safe and developmentally appropriate food is essential to child health. Inappropriate complementary foods and feeding practices are ... -
Complementary feeding practices and the risk of exposure to aflatoxins among infants and young children in Kongwa, Tanzania
(NM-AIST, 2022-08)Aflatoxins (AFs) are secondary fungal metabolites that commonly contaminate foods like nuts and cereals and pose major public health concerns like impaired child growth, immune system suppression, liver cancer and death. ... -
A computational study on the role of solvents and conformational fluctuation of macromolecules towards drug design
(NM-AIST, 2020-04)Heat shock protein 90 (Hsp90) represents an important chemotherapeutic target in the treatment of various ailments including cancer and neurodegenerative diseases. The protein is responsible for controlling and regulating ... -
Cone Bioassays Provide Reproducible Bioefficacy Estimates with Different Anopheline Mosquitoes and Can Be Used for Quality Assurance of Pyrethroid Insecticide Treated Nets
(Research Square, 2022-01-24)Background Quality assurance (QA) of insecticide-treated nets (ITNs) delivered to malaria-endemic countries is conducted by measuring physiochemical parameters, but not bioecacy against malaria mosquitoes. The cone ... -
Conjugative plasmids disseminating ctx-m-15 among enterobacteriaceae from human, animals and the environment in Mwanza Tanzania: a need to intensify one health approach
(NM-AIST, 2021-08)Globally, blaCTX-M-15 beta-lactamases are the most popular extended spectrum beta-lactamase alleles that are widely distributed due its mobilization by mobile genetic elements in several compartments. We aimed to determine ... -
Conjugative Plasmids Disseminating CTX-M-15 among Human, Animals and the Environment in Mwanza Tanzania: A Need to Intensify One Health Approach
(MDPI, 2021-07-09)Background: Globally, blaCTX-M-15 beta-lactamases are the most popular extended spectrum beta-lactamase alleles that are widely distributed due its mobilisation by mobile genetic elements in several compartments. We aimed ... -
Connectivity between land, water, and people: integrating process concepts and assessment evidence across disciplines for co-design of soil erosion solutions
(Authorea, 2020-04-20)Soil resources in East Africa are being rapidly depleted by erosion, threatening food-, water- and livelihood security in the region. Here we demonstrate how integration of evidence from natural and social sciences has ... -
Conservation and Management Challenges Facing a Medicinal Plant Zanthoxylum chalybeum in Simanjiro Area, Northern Tanzania
(MDPI, 2020-05-19)The information on the medicinal use, availability, challenges, and future conservation strategies for the medicinal plant Zanthoxylum chalybeum were gathered by using a semi-structured questionnaire, focused group ... -
Conservation and Management Challenges Facing a Medicinal Plant Zanthoxylum chalybeum in Simanjiro Area, Northern Tanzania
(MDPI, 2020-05-19)The information on the medicinal use, availability, challenges, and future conservation strategies for the medicinal plant Zanthoxylum chalybeum were gathered by using a semi-structured questionnaire, focused group ... -
Conservation of forest biomass and forest–dependent wildlife population: Uncertainty quantification of the model parameters
(Elsevier, 2023)The ecosystem is confronted with numerous challenges as a consequence of the escalating human population and its corresponding activities. Among these challenges lies the degradation of forest biomass, which directly ... -
Conserved, breed-dependent, and subline-dependent innate immune responses of Fayoumi and Leghorn chicken embryos to Newcastle disease virus infection.
(Scientific Reports, 2019-05-10)Newcastle disease virus (NDV) is a threat to the global poultry industry, but particularly for smallholder farmers in low- and middle-income countries. Previous reports suggest that some breeds of chickens are less susceptible ... -
Constraints to utilization of the African nightshades and the effects of lactic acid fermentation on its nutritional and sensory qualities
(NM-AIST, 2023-08)African nightshades (ANS, Solanum nigrum complex) are among the most widely distributed and consumed indigenous vegetables in Tanzania. Several challenges hamper the utilization of ANS. This study sought to assess ... -
Consumers’ product knowledge and attitudes as determinants of buying intention of processed sardine product: case of lake Victoria basin
(African Journal of Emerging Issues, 2019-08-08)Purpose of the study: This paper highlights the determinants of consumers’ buying behavior of processed sardine products from Lake Victoria basin by determining consumers’ knowledge and attitudes in relation to buying ... -
Context-specific food-based approach for ensuring nutrition security in developing countries: a review
(Taylor & Francis Online, 2017-09-17)Sustainable food strategies for meeting nutrient needs in developing countries are not well established. The available evidence shows that more than one-third of the world’s population is facing under-nutrition, of which ...