Insulin-delivery methods for children and adolescents with type 1 diabetes

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dc.contributor.author Zuberi, Zavuga
dc.contributor.author Sauli, Elingarami
dc.contributor.author Cun, Liu
dc.contributor.author Deng, Jing
dc.contributor.author Li, , Wen-Jun
dc.contributor.author He, Xu-Liang
dc.contributor.author Li, Wen
dc.date.accessioned 2020-06-02T12:31:16Z
dc.date.available 2020-06-02T12:31:16Z
dc.date.issued 2020-05-08
dc.identifier.uri https://doi.org/10.1177%2F2042018820906016
dc.identifier.uri https://dspace.nm-aist.ac.tz/handle/123456789/762
dc.description This research article published by Sage Journal, 2020 en_US
dc.description.abstract Efforts directed toward restoring normal metabolic levels by mimicking the physiological insulin secretion, thereby ensuring safety, efficacy, minimal invasiveness and conveniences, are of great significance in the management of type 1 diabetes among children and adolescents. Regardless of the various technologies being discovered in addressing invasiveness and enhancing medication adherence in the management of type 1 diabetes, yet limited success had been observed among children and adolescents. The multiple daily subcutaneous insulin injections route using vial and syringe, and occasionally insulin pens, remain the most predictable route for insulin administration among children and adolescents. However, this route has been associated with compromised patient compliance, fear of injections and unacceptability, resulting in poor glycemic control, which promote the demand for alternative routes of insulin administration. Alternative routes for delivering insulin are being investigated in children and adolescents with type 1 diabetes; these include the hybrid closed-loop ‘artificial pancreas’ system, oral, inhalation, intranasal routes, and others. This review article explores the current advances in insulin-delivery methods that address the needs of children and adolescents in the treatment of type 1 diabetes. en_US
dc.language.iso en en_US
dc.publisher Sage Journal en_US
dc.subject Artificial pancreas en_US
dc.subject Insulin delivery en_US
dc.subject Nasal insulin en_US
dc.subject Type 1 diabetes en_US
dc.title Insulin-delivery methods for children and adolescents with type 1 diabetes en_US
dc.type Article en_US

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