Browsing by Author "Vuai, Said"
Now showing items 1-9 of 9
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Abrogating the nsp10–nsp16 switching mechanisms in SARS-CoV-2 by phytochemicals from Withania somnifera: a molecular dynamics study
Vuai, Said; Onoka, Isaac; Sahini, Mtabazi; Swai, Hulda; Shadrack, Daniel (Taylor & Francis Online, 2021-09-14)The search for therapeutic small molecules and vaccines for Covid-19 treatment is an urgent but evolving topic. The virus has claimed over 3,782,490 lives (as of 12 June 2021), with the figure expected to rise due to the ... -
Antibiotic-resistant microbial populations in urban receiving waters and wastewaters from Tanzania
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Miraji, Hossein; Bih, Numfor; Mzula, Alexanda; Mwega, Elisa; Njau, Karoli; Vuai, Said; Machunda, Revocatus (Elsevier, 2023)Antimicrobial resistance against certain medications in the pathogenic microbial community is globally increasing due to the continual discharge and disposal of pharmaceuticals in the environment. The phenomenon resulted ... -
Combatting toxic chemical elements pollution for Sub-Saharan Africa's ecological health
Ripanda, Asha; Hossein, Miraji; Rwiza, Mwemezi; Nyanza, Elias; Selemani, Juma; Nkrumah, Salma; Bakari, Ramadhani; Alfred, Mateso; Machunda, Revocatus; Vuai, Said (Elsevier, 2025-02-08)With its booming mining, processing industries, agriculture, and increasing urbanization, sub-Saharan Africa experiences an alarming rise in accumulation of toxic chemical elements in all environmental matrices threatening ... -
Contribution of Illicit Drug Use to Pharmaceutical Load in the Environment: A Focus on Sub-Saharan Africa
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Machunda, Revocatus; Vuai, Said (Hindawi, 2022-07-08)Illicit drug abuse and addiction are universal issues requiring international cooperation and interdisciplinary and multisectoral solutions. ese addictive substances are utilized for recreational purposes worldwide, ... -
Data from the batch adsorption of ciprofloxacin and lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar: Response surface methodology (RSM) optimization
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Bakari, Ramadhani; Miraji, Hossein; Njau, Karoli; Vuai, Said; Machunda, Revocatus (Elsevier, 2023-02)This dataset expresses the experimental data on the batch adsorption of ciprofloxacin and lamivudine from synthetic solution using jamun seed (JS) (Syzygium cumini) biochar. Independent variables including concentration ... -
Ecological Consequences of Antibiotics Pollution in Sub-Saharan Africa: Understanding Sources, Pathways, and Potential Implications
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Hossein, Miraji; Alfred, Mateso; Mahmoud, Alaa; Murthy, Ananda; Bakari, Ramadhani; Vuai, Said; Machunda, Revocatus (KeAi, 2025-01-25)In Sub-Saharan Africa (SSA), the increasing use of antibiotics in human and veterinary medicine, combined with inadequate waste and water management systems, has intensified the problem of antibiotic pollution. Untreated ... -
Relaxed complex scheme and molecular dynamics simulation suggests small molecule inhibitor of human TMPRSS2 for combating COVID-19
Vuai, Said; Ogedjo, Marcelina; Onoka, Isaac; Sahini, Mtabazi; Swai, Hulda; Shadrack, Daniel (Taylor & Francis online, 2021-11-09)As the coronavirus disease 19 (COVID-19) pandemic continues to pose a health and economic crisis worldwide, the quest for drugs and/or vaccines against the virus continues. The human transmembrane protease serine 2 (TMPRSS2) ... -
Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Bakari, Ramadhani; Bakari, Ramadhani; Miraji, Hossein; Njau, Karoli; Vuai, Said; Machunda, Revocatus (Emerging Contaminants, 2023-09-01)Antiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity. Following therapeutic uses, approximately 70% of the oral ... -
A Review on Contaminants of Emerging Concern in the Environment: A Focus on Active Chemicals in Sub-Saharan Africa
Ripanda, Asha; Rwiza, Mwemezi; Nyanza, Elias; Njau, Karoli; Vuai, Said; Machunda, Revocatus (MDPI, 2021-12-22): Active chemicals are among the contaminants of emerging concern that are rarely covered in regulatory documents in sub-Saharan Africa. These substances are neither in the list of routinely monitored substances nor in ...