Browsing by Author "Verschoor, Jan A."

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Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis

Lemmer, Yolandy; Kalombo, Lonji; Pietersen, Ray-Dean; Jones, Arwyn T.; Semete-Makokotlela, Boitumelo; Van Wyngaardt, Sandra; Ramalapa, Bathabile; Stoltz, Anton C.; Baker, Bienyameen; Verschoor, Jan A.; Swai, Hulda; de Chastellier, Chantal (Elsevier, 2015-06-06)

The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
Spray-Dried, Nanoencapsulated, Multi-Drug Anti-Tuberculosis Therapy Aimed at OnceWeekly Administration for the Duration of Treatment

Kalombo, Lonji; Lemmer, Yolandy; Semete-Makokotlela, Boitumelo; Ramalapa, Bathabile; Nkuna, Patric; Booysen, Laetitia L.L.I.J.; Naidoo, Saloshnee; Hayeshi, Rose; Verschoor, Jan A.; Swai, Hulda (MDPI, 2019-08-15)

Aiming to improve the treatment outcomes of current daily tuberculosis (TB) chemotherapy over several months, we investigated whether nanoencapsulation of existing drugs would allow decreasing the treatment frequency to ...