Browsing by Author "Sabi, Issa"

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N-acetylcysteine modulates markers of oxidation, inflammation and infection in tuberculosis

Mapamba, Daniel; Sabi, Issa; Lalashowi, Julieth; Sauli, Elingarami; Buza, Joram; Olomi, Willyhelmina; Mtafya, Bariki; Kibona, Michael; Velen, Kavindhran; Hoelscher, Michael (Elsevier, 2025-01-03)

Background Half the global tuberculosis health burden is due to post-tuberculosis lung disease. Host-directed therapies have been proposed to reduce this burden. N-acetylcysteine (NAC) provides the conditionally essential ...
Performance of Tuberculosis Molecular Bacterial Load Assay Compared to Alere TB-LAM in Urine of Pulmonary Tuberculosis Patients with HIV Co-Infections

Mapamba, Daniel; Sauli, Elingarami; Lalashowi, Julieth; Buza, Joram; John, Joseph; Mwaisango, Zawadi; Tarmo, Peter; Sabi, Issa; Rachow, Andrea; Ntinginya, Nyanda; Mtafya, Bariki (MDPI, 2023-02-23)

Alternative tools are needed to improve the detection of M. tuberculosis (M. tb) in HIV co-infections. We evaluated the utility of Tuberculosis Molecular Bacterial Load Assay (TB-MBLA) compared to lipoarabinomannan (LAM) ...