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dc.contributor.authorBuza, Joram
dc.contributor.authorHikono, Hirokazu
dc.contributor.authorMori, Yasuyuki
dc.contributor.authorReiko, Nagata
dc.contributor.authorHirayama, Sachiyo
dc.contributor.authorBari, Abusaleh
dc.contributor.authorGeril, Aodon
dc.contributor.authorShu, Yujing
dc.contributor.authorTsuji, Noriko
dc.contributor.authorMomotani, Eiichi
dc.date.accessioned2019-10-07T12:49:17Z
dc.date.available2019-10-07T12:49:17Z
dc.date.issued2014-04
dc.identifier.uri
dc.identifier.urihttp://dspace.nm-aist.ac.tz/handle/123456789/461
dc.descriptionResearch Article published American Society for Microbiology. All Rights Reserved Vol. 72, No. 4en_US
dc.description.abstractMonoclonal antibody neutralization of interleukin-10 (IL-10) increased Johnin purified protein derivativeinduced whole-blood gamma interferon (IFN- ) secretion 23-fold and also increased IFN- secretion ninefold following in vitro Mycobacterium avium subsp. paratuberculosis infection of peripheral blood mononuclear cells. These results demonstrate the suppressive effect of IL-10 on immune responses to M. avium subsp. paratuberculosis infection in cattle.en_US
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titleNeutralization of Interleukin-10 Significantly Enhances Gamma Interferon Expression in Peripheral Blood by Stimulation with Johnin Purified Protein Derivative and by Infection with Mycobacterium avium subsp. paratuberculosis in Experimentally Infected Cattle with Paratuberculosisen_US
dc.typeArticleen_US


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