Browsing Life sciences and Bio-engineering by Subject "In vitro drug release"

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Enhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method.

Tshweu, Lesego; Katata, Lebogang; Kalombo, Lonji; Chiappetta, Diego; Hocht, Christian; Sosnik, Alejandro; Swai, Hulda (NANOMEDICINE, 2014-10-17)

Aim: To encapsulate efavirenz (EFV) within poly(epsilon-caprolactone) (PCL) nanoparticles (NPs) and compare the oral pharmacokinetics with that of EFV-loaded micelles and pure EFV NPs. Materials & methods: EFV-loaded PCL ...