Browsing Life sciences and Bio-engineering by Author "Haydon, Daniel"
Now showing items 1-17 of 17
-
Complete genome sequence of Brucella abortus isolated from a human blood culture sample in Tanzania
(American society for microbiology, 2024-01-30)Brucella abortus causes infections in humans and livestock. Bacterial isolates are challenging to obtain, and very little is known about the genomic epidemiology of this species in Africa. Here, we report the complete ... -
Integrating contact tracing and whole- genome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study
(eLife Sciences Publications Ltd, 2023-05-25)Background: Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass ... -
Integrating contact tracing and wholegenome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study
(eLife, 2023-05-23)Background: Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass ... -
Integrating serological and genetic data to quantify cross-species transmission: brucellosis as a case study
(Cambridge University Press, 2016-03-03)Epidemiological data are often fragmented, partial, and/or ambiguous and unable to yield the desired level of understanding of infectious disease dynamics to adequately inform control measures. Here, we show how the ... -
Latent class evaluation of the performance of serological tests for exposure to Brucella spp. in cattle, sheep, and goats in Tanzania
(PLOS Medicine, 2021-08-24)Brucellosis is a neglected zoonosis endemic in many countries, including regions of sub-Saharan Africa. Evaluated diagnostic tools for the detection of exposure to Brucella spp. are important for disease surveillance and ... -
Low topotype diversity of recent foot-and-mouth disease virus serotypes O and A from districts located along the Uganda and Tanzania border.
(The Korean Society of Veterinary Science, 2019-03-01)Foot-and-mouth disease (FMD) is one of the most important livestock diseases in East Africa with outbreaks reported annually that cause severe economic losses. It is possible to control disease using vaccination, but ... -
Molecular detection and genetic characterization of Bartonella species from rodents and their associated ectoparasites from northern Tanzania
(PLOS ONE, 2019-10-15)Background Bartonellae are intracellular bacteria, which can cause persistent bacteraemia in humans and a variety of animals. Several rodent-associated Bartonella species are human pathogens but data on their global ... -
Molecular detection of Coxiella burnetii infection in small mammals from Moshi Rural and Urban Districts, northern Tanzania.
(John Wiley & Sons Ltd, 2020-12-05)Coxiella burnetii is an obligate intracellular bacterium that causes Q fever, a zoonotic disease of public health importance. In northern Tanzania, Q fever is a known cause of human febrile illness, but little is known ... -
Occurrence of Foot-and-Mouth Disease Virus Serotypes in Uganda and Tanzania (2003 to 2015): A Review and Implications for Prospective Regional Disease Control
(Journal of Agricultural Science, 2020-05-15)Endemic foot-and-mouth disease (FMD) presents a global economic challenge to the livestock industry. The progressive control pathway for FMD (PCP-FMD) specifies successive steps through which a country/region can reduce ... -
One Health contributions towards more effective and equitable approaches to health in low- and middle-income countries
(Published by the Royal Society, 2017)Emerging zoonoses with pandemic potential are a stated priority for the global health security agenda, but endemic zoonoses also have a major societal impact in low-resource settings. Although many endemic zoonoses can ... -
One Health in Practice: Using Integrated Bite Case Management to Increase Detection of Rabid Animals in Tanzania.
(Frontiers in Public Health, 2020-02-14)Rabies is a neglected zoonotic disease that causes an estimated 59,000 human deaths worldwide annually, mostly in Africa and Asia. A target of zero human deaths from dog-mediated rabies has been set for 2030, and large-scale ... -
Prevalence and risk factors for human leptospirosis at a hospital serving a pastoralist community, Endulen, Tanzania
(PLOS Neglected Tropical Diseases, 2023-12-20)Background Leptospirosis is suspected to be a major cause of illness in rural Tanzania associated with close contact with livestock. We sought to determine leptospirosis prevalence, identify infecting Leptospira serogroups, ... -
Prevalence and risk factors for Q fever, spotted fever group rickettsioses, and typhus group rickettsioses in a pastoralist community of northern Tanzania, 2016–2017
(John Wiley & Sons Ltd., 2024-01-12)Background: In northern Tanzania, Q fever, spotted fever group (SFG) rickettsioses, and typhus group (TG) rickettsioses are common causes of febrile illness. We sought to describe the prevalence and risk factors for these ... -
Prevalence and speciation of brucellosis in febrile patients from a pastoralist community of Tanzania.
(Springer Nature Limited, 2020-04-27)Brucellosis is an endemic zoonosis in sub-Saharan Africa. Pastoralists are at high risk of infection but data on brucellosis from these communities are scarce. The study objectives were to: estimate the prevalence of human ... -
Reservoir dynamics of rabies in south-east Tanzania and the roles of cross-species transmission and domestic dog vaccination
(John Wiley & Sons, Inc., 2021-08-21)Understanding the role of different species in the transmission of multi-host pathogens, such as rabies virus, is vital for effective control strategies. Across most of sub-Saharan Africa domestic dogs Canis familiaris are ... -
Spatial and temporal distribution of foot-and-mouth disease in four districts situated along the Uganda-Tanzania border: Implications for cross-border efforts in disease control.
(AOSIS, 2018-08-27)Foot-and-mouth disease (FMD) is one of the major trans-boundary animal diseases in East Africa causing economic loss to farmers and other stakeholders in the livestock industry. Foot-and-mouth disease occurs widely in both ... -
Tracking animal movements using biomarkers in tail hairs: a novel approach for animal geolocating from sulfur isoscapes.
(Movement Ecology, 2020-09-18)Background Current animal tracking studies are most often based on the application of external geolocators such as GPS and radio transmitters. While these technologies provide detailed movement data, they are costly to ...
