Understanding the persistence of plague foci in Madagascar.

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dc.contributor.author Andrianaivoarimanana, Voahangy
dc.contributor.author Kreppel, Katharina
dc.contributor.author Elissa, Nohal
dc.contributor.author Duplantier, Jean-Marc
dc.contributor.author Carniel, Elisabeth
dc.contributor.author Rajerison, Minoarisoa
dc.contributor.author Jambou, Ronan
dc.date.accessioned 2020-01-23T09:34:40Z
dc.date.available 2020-01-23T09:34:40Z
dc.date.issued 2013-11-01
dc.identifier.other 24244760
dc.identifier.uri doi: 10.1371/journal.pntd.0002382
dc.identifier.uri http://dspace.nm-aist.ac.tz/handle/123456789/535
dc.description Research Article published by PLOS Neglected Tropical Diseases, Volume 7, Issue 11, November 2013 en_US
dc.description.abstract Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar. en_US
dc.language.iso en en_US
dc.publisher PLOS Neglected Tropical Diseases en_US
dc.subject Research Subject Categories::NATURAL SCIENCES en_US
dc.title Understanding the persistence of plague foci in Madagascar. en_US
dc.type Article en_US

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