Browsing by Author "Sauli, Elingarami"
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Application of Nanotechnology in Enhancing Efficacy of African Herbal Medicines-A review
Sauli, Elingarami; Lema, Witness (MDPI, 2025)African herbal medicine has been used for centuries as a means of treating various ailments. However, limitations in the effectiveness and delivery of these herbal remedies have necessitated exploration of alternative ... -
Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania
Kapeleka, Jones; Sauli, Elingarami; Sadik, Omowunmi; Ndakidemi, Patrick (Hindawi, 2019-09-11)Biomonitoring of pesticides exposure has currently become a matter of great public concern due to the potential health effects of pesticides. ,is study assessed levels of acetylcholinesterase (AChE) inhibition and associated ... -
Blood cytokine responses to early secreted protein antigen-6/culture filtrate protein-10 tuberculosis antigens 2 months after antituberculosis treatment among patients with drug-susceptible pulmonary tuberculosis.
Mvungi, Happiness; Mbelele, Peter; Buza, Joram; Mpagama, Stellah; Sauli, Elingarami (Wolters Kluwer - Medknow, 2019-03-12)Background: Human tuberculosis is a chronic inflammatory disease caused by mycobacterium tuberculosis. Pulmonary tuberculosis is the result of the failure of host immune system to control mycobacterium tuberculosis. The ... -
Cardiovascular diseases in Tanzania: The burden of modifiable and intermediate risk factors
Roman, Wilfrida; Martin, Haikael; Sauli, Elingarami (AME Publishing Company, 2019-08-27)Abstract: Tanzania, like other developing countries, is facing a higher burden of cardiovascular diseases (CVDs). The country is experiencing rapid growth of modifiable and intermediate risk factors that accelerate CVD ... -
Causal relationship between Environmental Enteric Dysfunction (EED), poor WaSH practices and growth failure in children from Rukwa-Tanzania
Modern, Grantina; Mpolya, Emmanuel; Sauli, Elingarami (Elsevier, 2022-07)Stunting is the most prevalent form of chronic undernutrition. The Rukwa region in Tanzania has one of the highest prevalence of stunting, despite being one of the most food secure region in the country. It is therefore ... -
Changing Patterns and Drivers of Increased Pesticides Use in Smallholder Vegetable Production Systems in Tanzania
Kapeleka, Jones A.; Sauli, Elingarami; Sadik, Omowunmi; Ndakidemi, Patrick A. (BioRxiv, 2021-01-18)Pesticides use has become a key component of smallholder horticulture production. Therefore, dynamics in pesticides handling need to be ascertained. This study assessed drivers of pesticides use and determinants of changing ... -
Co-exposure risks of pesticides residues and bacterial contamination in fresh fruits and vegetables under smallholder horticultural production systems in Tanzania
Kapeleka, Jones; Sauli, Elingarami; Sadik, Omowunmi; Ndakidemi, Patrick (PLOS ONE, 2020-07-25)This study was carried out to investigate the risks of simultaneous exposure to pesticide residues and bacteria contaminants in locally produced fresh vegetables and vegetables in Tanzania. A total of 613 samples were ... -
Consumption of Mixed Indigenous Vegetables: A solution to low hemoglobin levels among pregnant women in Babati, Tanzania
Malley, Zuwena; Sauli, Elingarami; Martin, Haikael (Enviro Research Publishers., 2025-02-25)Pregnancy-related anemia is a critical health issue affecting a larger number of pregnant women in Tanzania affected. The study examined the impact of consuming locally grown indigeneous vegetables on iron intake and anemia ... -
Correlates of diarrhea and stunting among under-five children in Ruvuma, Tanzania; a hospital-based cross-sectional study
Modern, Grantina; Sauli, Elingarami; Mpolya, Emmanuel (Elsevier, 2020-07)Undernutrition affects 20% of children under five in the developing world. Stunting is a form of undernutrition when children have low height for their age. Global prevalence of stunting in 2019 was 21.4%, while current ... -
Dengue virus transmission during non-outbreak period in Dar Es Salaam, Tanzania: a cross-sectional survey
Mustafa, Ummul-khair; Kreppel, Katharina; Sauli, Elingarami (Springer Nature, 2024-10-29)Background Tanzania has experienced multiple dengue outbreaks between 2010 and 2019, caused by various dengue virus (DENV) strains. In 2019, there were 6917 confirmed dengue cases and 13 deaths in Tanzania. Routine diagnosis ... -
Development and Validation of a Mobile Game for Culturally Sensitive Child Sexual Abuse Prevention Education in Tanzania: Mixed Methods Study
Malamsha, Maria; Sauli, Elingarami; Luhanga, Edith (JMIR SERIOUS GAMES, 2021-11-08)Background: Globally, 3 out of 20 children experience sexual abuse before the age of 18 years. Educating children about sexual abuse and prevention is an evidence-based strategy that is recommended for ending child sexual ... -
Development and Validation of a Mobile Game for Culturally Sensitive Child Sexual Abuse Prevention Education in Tanzania: Mixed Methods Study
Malamsha, Maria; Sauli, Elingarami; Luhanga, Edith (JMIR Publications Inc., Toronto, Canada, 2021-05-13)Background: Globally, 3 out of 20 children experience sexual abuse before the age of 18 years. Educating children about sexual abuse and prevention is an evidence-based strategy that is recommended for ending child sexual ... -
Digital Technologies to Enhance Infectious Disease Surveillance in Tanzania: A Scoping Review
Mustafa, Ummul-khair; Kreppel, Katharina; Brinkel, Johanna; Sauli, Elingarami (MDPI, 2023-02-06)Mobile phones and computer-based applications can speed up disease outbreak detection and control. Hence, it is not surprising that stakeholders in the health sector are becoming more interested in funding these technologies ... -
Efficiency of honey–grape blend in reducing radiation-induced mucositis in locally advanced head and neck squamous cell carcinoma
Kyomo, Magaisha; Mpumi, Nelson; Sauli, Elingarami; Lidenge, Salum (AIMS Press, 2025-03-12)This study assessed the efficacy of a honey–grape blend in reducing the severity and onset of radiation oral mucositis (ROM) in patients with locally advanced squamous cell carcinoma of the head and neck. Oral mucositis ... -
Expression analysis of p16 and TOP2A protein biomarkers in cervical cancer lesions and their correlation with clinico-histopathological characteristics in a referral hospital, Tanzania
Zuberi, Zavuga; Mremi, Alex; Chilongola, Jaffu; Semango, George; Sauli, Elingarami (PLOS ONE, 2021-10-27)Introduction Biomarkers yield important information for early diagnosis of cervical cancer. However, they are rarely applied for prognosis of cervical cancer in Tanzania, where visual inspection assay with acetic acid ... -
The extended scope of neuroimaging and prospects in brain atrophy mitigation: a systematic review
Sungura, Richard; Onyambu, Callen; Mpolya, Emmanuel; Sauli, Elingarami; Vianney, John-Mary (Elsevier B.V., 2020-08-15)Brain atrophy is a condition associated with a reduction of brain volume. It is a common manifestation of aging even though it occurs in some childhood conditions and carried forward to pre-senile middle age. There are ... -
Formulation, Optimization, and Evaluation of Moringa oleifera Leaf Polyphenol-Loaded Phytosome Delivery System against Breast Cancer Cell Lines
Wanjiru, Jecinta; Gathirwa, Jeremiah; Sauli, Elingarami; Swai, Hulda (MDPI, 2022-07-11)Moringa oleifera leaf polyphenols (Mopp) were encapsulated with phytosomes to enhance their efficacy on 4T1 cancer cell lines. The Mopp were extracted via microwave-assisted extraction. Moringa oleifera polyphenol-loaded ... -
Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer
Wegman, Pia; Sauli, Elingarami; Carstensen, John; Stål, Olle; Wingren, Sten (Springer Nature, 2007-01-23)Introduction Tamoxifen therapy reduces the risk of recurrence and prolongs the survival of oestrogen-receptor-positive patients with breast cancer. Even if most patients benefit from tamoxifen, many breast tumours either ... -
Genomic characterization of methicillin-resistant Staphylococcus aureus isolated from patients attending regional referral hospitals in Tanzania
Geofrey, Mujungu; Sauli, Elingarami; Kanje, Livin; Beti, Melkiory; Shayo, Mariana; Kuchaka, Davis; Zwetselaar, Marco; Wadugu, Boaz; Mmbaga, Blandina; Mkumbaye, Sixbert; Kumburu, Happiness; Sonda, Tolbert (BioMed Central, 2024-08-14)Background Methicillin-resistant Staphylococcus aureus (MRSA) colonization increases the risk of subsequent infection by MRSA strain complex interlinking between hospital and community-acquired MRSA which increases the ... -
Health professionals’ knowledge on dengue and health facility preparedness for case detection: A cross-sectional study in Dar es Salaam, TanzaniaHealth professionals’ knowledge on dengue and health facility preparedness for case detection: A cross-sectional study in Dar es Salaam, Tanzania
Mustafa, Ummul-khair; Sauli, Elingarami; Brinkel, Johanna; Kreppel, Katharina (PLOS, 2023-11-21)Dengue presents a growing public health concern in the Dar es Salaam region of Tanzania, marked by the recurring incidence of outbreaks. Unfortunately, there is little information available on the region’s preparedness in ...