Browsing by Author "Olomi, Willyhelmina"

Now showing items 1-2 of 2

    • Impact of N-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients—A Systematic Review 

      Mapamba, Daniel; Sauli, Elingarami; Mrema, Lucy; Lalashowi, Julieth; Magombola, David; Buza, Joram; Olomi, Willyhelmina; Wallis, Robert; Ntinginya, Nyanda (MDPI, 2022-11-21)
      Sustained TB infection overproduces reactive oxygen species (ROS) as a host defense mechanism. Research shows ROS is destructive to lung tissue. Glutathione (GSH) neutralizes ROS, although it is consumed. NAC is a precursor ...

    • N-acetylcysteine modulates markers of oxidation, inflammation and infection in tuberculosis 

      Mapamba, Daniel; Sabi, Issa; Lalashowi, Julieth; Sauli, Elingarami; Buza, Joram; Olomi, Willyhelmina; Mtafya, Bariki; Kibona, Michael; Velen, Kavindhran; Hoelscher, Michael (Elsevier, 2025-01-03)
      Background Half the global tuberculosis health burden is due to post-tuberculosis lung disease. Host-directed therapies have been proposed to reduce this burden. N-acetylcysteine (NAC) provides the conditionally essential ...